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What is analytical chemistry?. 5 subdisciplines of chemistry Some definitions In every day life… Analytical chemist versus chemical analyst. “My” steps. Formulate the question Select analytical procedures Sampling** “Representative” sample Homogeneous versus heterogeneous
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What is analytical chemistry? • 5 subdisciplines of chemistry • Some definitions • In every day life… • Analytical chemist versus chemical analyst
“My” steps • Formulate the question • Select analytical procedures • Sampling** • “Representative” sample • Homogeneous versus heterogeneous • Sample Preparation** Most analyses require a liquid solution: • Extraction • Digestion • Analysis • What type of analysis? • Manipulate data • Statistical analysis • Interpret results/draw conclusions • Communicate results
Types of Analyses • Qualitative analysis • Quantitative analysis • Characterization analysis • Fundamental analysis
Some Terminology • Analyte • Matrix • Analysis– Measurement –Determination • Technique – Method – Procedure – Protocol
Classifying Techniques • All analyses based on a signal • Total Analysis Technique • AKA “Classical Method” • Concentration Technique • AKA “Instrumental Method”
Method Considerations:Analytical Figures of Merit (AFOMs) • Accuracy • Precision • Sensitivity • Selectivity • Robustness • Ruggedness • Scale of operation, • Analysis time • Availability of equipment • Cost
Relevant Reading • Chpt 1 all • Chpt 3 to 3C • Chpt 2 (review)