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NITROGEN METABOLISM

NITROGEN METABOLISM. Nitrogen is essential for all organisms (in amino acids and nucleic acids). Most of the conversions between organic and inorganic nitrogen are catalyzed by bacterial and archaeal enzymes. oxidative. reductive. fungi. plants. animals. Urea cycle:

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NITROGEN METABOLISM

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  1. NITROGEN METABOLISM

  2. Nitrogen is essential for all organisms (in amino acids and nucleic acids). Most of the conversions between organic and inorganic nitrogen are catalyzed by bacterial and archaeal enzymes. oxidative reductive fungi plants animals

  3. Urea cycle: Lose two amino-N and a CO2 Follow the N from carbamoyl-P (green arrow) and the N from aspartate (red arrow). How much energy does it take to remove two amino-nitrogens?

  4. How many of the reactions that we have studied are represented in excretion of excess nitrogen?

  5. Summary • Nitrogen enters the biosphere through plants, fungi, but mainly • bacteria and archaea • Plants, fungi, and bacteria reduce nitrate nitrogen to ammonium • Ammonium is incorporated into organic molecules by glutamate • dehydrogenase and glutamine synthase/GOGAT • Other amino acids are formed by transamination • The urea cycle removes nitrogen from ammonia and alanine • as urea

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