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PROBIOTICS AS GROWTH PROMOTERS. Dr.K.Geetha , Assistant Professor, Nanotechnology Division/Dept Of ECE, PMIST. TABLE OF CONTENTS. PROBIOTICS & GROWTH PROMOTERS DEFINITION CLASSIFICATION MICRO ORGANISMS USED IN PROBIOTICS PROBIOTIC APPLICATIONS IN DIFFERENT LIVESTOCK
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PROBIOTICS AS GROWTH PROMOTERS Dr.K.Geetha, Assistant Professor, Nanotechnology Division/Dept Of ECE, PMIST
TABLE OF CONTENTS • PROBIOTICS & GROWTH PROMOTERS DEFINITION • CLASSIFICATION • MICRO ORGANISMS USED IN PROBIOTICS • PROBIOTIC APPLICATIONS IN DIFFERENT LIVESTOCK • BENEFITS AND RISKS
GROWTH PROMOTERS • DEFINITION: • Growth Promoters are the substances used to increase the feed conversion efficiency, average daily gain and milk production of animals. • TYPES OF GROWTH PROMOTERS: • Feed additives • Hormonal implants • Growth Hormones • Repartitioning agents • Probiotics
PROBIOTICS : DEFINITION AND CLASSIFICATION DEFINITION: ‘’ Organisms which contribute to intestinal microbial balance’’. The joint WHO & FAO working group defined probiotics as ‘’ live micro-organisms when administered in adequate amounts, confer health benefit on host’’. This definition is widely accepted and adopted by the International Scientific Association for Probiotics & Prebiotics
Cont…. • Effects of probiotic depends on: • The combination of selected microbial genera • Doses • Feed composition • Storage conditions
CLASSIFICATIONS OF PROBIOTICS • Bacterial Probiotics: • Eg: Lactobacillus, Bifidobacterium, Bacillus and Enterococcus. • Non-Bacterial Probiotics: • Eg: Aspergillusoryzae, Candida pintolopessii, Saccharomyces boulrlardii
Cont…. • Multi-species Probiotics: • Eg: PoultryStarME (contains Enterococcus faecium, Lactobacillus reuteri, L. salivariusandPediococcusacidilactici), PrimaLac(contains Lactobacillus spp., E. faecium, andBifidobacteriumthermophilum) and Microguard (contains various species of Lactobacillus, Bacillus, Streptococcus, Bifidobacteriumand Saccharomyces.
Contd……. • Single-species Probiotics: • Eg: Bro-bio-fair (Saccharomyces), Anta Pro EF • (E. Faecium) • Allochthonous Probiotics: • The micro-organisms used as probiotics which are normally not present in the GIT of animals are referred to as allochthonous (e.g. yeasts)
Cont…… • Autochthonous Probiotics: • The micro-organisms normally present as indigenous inhabitants of the GIT are referred to as autochthonous probiotics (e.g. Lactobacillus andBifidobacterium).
THE FOLLOWING TABLE SHOWS PROBIOTICS THAT ARE COMMONY USED IN ANIMAL NUTRITION
ROLE OF PROBIOTICS IN ANIMAL INTESTINE • The immune response is stimulated and the activities of host antibodies are increased. • Probioticscompetes with pathogens for important nutrients in the gut. • Adhesion to the digestive tract wall prevent colonization by pathogenic micro-organisms. • Neutralization of enterotoxins produced by pathogenic bacteria that cause fluid loss.
Probiotics Application in Different Life Stocks • PROBIOTICS IN POULTRY • PROBIOTICS IN RUMINAT NUTRITION • PROBIOTICS IN PIG
PROBIOTICS IN POULTRY • Dietary supplementation of different strains of L.bulgaricushas increased the live weight gain, feed conversion ratios and reduced the mortality. • Growth rate, nutrient utilization and digestibility of feed have been improved by supplementation of effective microbes to broilers via water at 0.02% level. • Increased growth rate is associated with increased villus height, which increases the absorption of nutrients from the intestine.
PREVENTION OF ENTERIC PATHOGENS • During the first week of post- hatch, that the chick was most susceptible to salmonella infection which causes food poisoning, typhoid fever • These salmonella infection can be treated by the use of lactobacillus strain and intestinal bacteria from adult chicken which have an resistance to salmonella infantis. • Campylobacteriosis is an important zoonotic disease in poultry which can be inhibited by using the bacterial strains of L.salivarius, L.reuteriisolated from GIT of healthy chickens.
PROBIOTICS IN RUMINANTS • Cattle, sheep, goat, and deer are the animals which has ruminant digestive system. • Ruminant digestive system has a large stomach divided into four compartments: • Rumen • Reticulum • Omasum • Abomasum
Cont…. • Ruminants rely on the micro-organisms for digestion of roughages. • The rumen microorganisms are very diverse and consist of bacteria, protozoa, and fungi. • Bacteria are the most numerous rumen microorganisms, at approximately 1 billion bacteria per milliliter of rumen fluid. Bacteria are responsible for most feed digestion in the rumen.
Cont…. • Fungi contribute up to 8 percent of the total rumen microorganisms. Fungi are responsible for the digestion of cellulose and lignin in more resistant forages, such as barley straw. • Feed conversion and rate of gain in a ruminant are strongly affected by the type and number of microorganisms in the rumen. • The rumen must contain the appropriate proportions of certain types of microorganisms to maximize productivity.
PROBIOTICS IN RUMINANT NUTRITION • Mixture of micro-organisms L.reuteri, L.alimentarius, E. faecium& Bi. Bifidiumisolated from healthy goat and when fed to goats for eight weeks resulted in weight gain by 9%. • Strain of B.amyloliquefaciens when fed to dairy calves at the rate of 3.16*10^8 cfu per kg improved growth rate by 39% and increased feed efficiency by 14%.
Cont…… • L.acidophillusimproved digestibility of crude protein and neutral detergent fibre in lactating Holstein cows which resulted in increased milk production per day by 7.6% • Effect of yeast probiotics in all ruminant species showed overall average increase in body weight and organic matter digestibility by 0.8%.
PROBIOTICS IN PIG NUTRITION • Use of probiotics such as Bioplus 2B ( containing B. subtilis, B. licheniformis) enhanced the performance of pigs with no increase in production cost. • Bioplus2B improved weight gain by 8% and feed use efficiency by upto 10%. • Adding Bioplus 2B to the diet at the rate of 0.64*10^6 cfu/g feed reduced morbidity and mortality.
When piglets are infected with enterotoxigenicE.colithe feed intake was increaedupto 6%. In pigs probiotics increased the lactic acid bacteria and decreased Enterobacterium in the GIT . Cont……
RISK ASSOCIATED WITH PROBIOTICS • Infection of the animal fed the probiotic. • Release of infectious micro-organisms or noxious compounds to the environment. • Infection of the handlers of animal or animal feed. • Hyper stimulation of the immune system susceptible hosts. • Detrimental metabolic or toxic effects in the host due to the production of toxins by the micro-organisms contained in probiotics.
REFERENCES • The Use of Probiotics in Animal Nutrition • Hiruta Yirga* • HaramayaUniversity, School of Animal and Range Science, Dire Dawa, Ethiopia • A REVIEW OF USE OF PROBIOTIC AS GROWTH PROMOTER IN ANIMAL FEEDING • S.S.P. Silva B.V. Sc ,Ph.D & S.P.GunaratneB.V.Sc, Ph.D. • Effect of probiotic supplementation on organic feed to alternative antibiotic growth promoter on production performance and economics analysis of quail • W. P. Lokapirnasari1, A. R. Dewi2, A. Fathinah2, S. Hidanah1, N. Harijani3, Soeharsono4, B. Karimah2 and A. D. Andriani • The Role of Probiotics in the Poultry Industry . • M. LutfulKabir