190 likes | 419 Views
PRPP synthetase. Nucleoside phosphorylases. Phosphoribosyl transferases. The committed step of de novo purine nucleotide biosynthesis. Phosphoribosylamine synthase: cooperativity with respect to PRPP concentration & product inhibition. Outline of de novo purine nucleotide biosynthesis.
E N D
PRPP synthetase Nucleoside phosphorylases Phosphoribosyl transferases
The committed step of de novo purine nucleotide biosynthesis
Phosphoribosylamine synthase: cooperativity with respect to PRPP concentration & product inhibition
Outline of de novo purine nucleotide biosynthesis
Enzymes I. Ribonucleotide reductaseII. Nucleotide diphosphate kinase III. dCMP kinaseIV. dUTP diphosphohydrolaseV. dCMP deaminaseVI. Thymidylate synthaseVII. FH2 reductase