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MRI Validation: RRMS vs. SPMS in Comparison of Gender, Age, and Disease Duration - Stepwise Analysis

This study validates MRI findings in 50 RRMS and 51 SPMS patients, comparing brain parenchymal fraction (BPF) and T2 lesion volume in relation to gender, age, disease duration, and other factors using a stepwise analysis method. The research focuses on ICC values, BPF-T2 correlation, and natural clustering among different groups.

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MRI Validation: RRMS vs. SPMS in Comparison of Gender, Age, and Disease Duration - Stepwise Analysis

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  1. Discovery set: 10 RRMS (2) vs 9 SPMS (3) 7 MRI RRMS (2) vs 3 MRI SPMS (3)

  2. Validation 50 RRMS vs 51 SPMS 15 MRI RRMS (2) vs 14 MRI SPMS (3)

  3. Validation 50 RRMS vs 51 SPMS 15 MRI RRMS (2) vs 14 MRI SPMS (3)

  4. Validation 50 RRMS vs 51 SPMS 15 MRI RRMS (2) vs 14 MRI SPMS (3)

  5. RR(2) and SP(3) groups BPF T2 ICC

  6. BPF vs ICC in Female(1) and Male(0) ICC inRR(2) and SP(3) groups

  7. RR(2) and SP(3) groups BPF Age T2 T2 vs Age BPF vs Age

  8. RR(2) and SP(3) groups BPF vs Disease Duration T2 vs Disease Duration

  9. BPF vs T2, natural clustering

  10. BPF vs T2 Cutoff 3 Cutoff 2

  11. BPF vs T2 Cutoff 4 BPF in T groups T2 in T groups

  12. BPF vs T2 Cutoff 4 BPF in T groups T2 in T groups

  13. BPF vs T2 RR (2)SP(3) in F(1) and M(0)

  14. stepwise (A, GROUP) RR vs SP A=[GENDER, AGE, ICC, T2, BPF, CSF, DD, DIS_ACT, T]

  15. A=[GENDER, AGE, ICC, T2, BPF, CSF, DD, DIS_ACT, T] in RR(2)SP(3)

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