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Figure 15.2 A Model Signal Transduction Pathway

Figure 15.2 A Model Signal Transduction Pathway. Outer membrane of bacterium. Cell wall. Intermembrane space. Plasma membrane. Pores. Environment. Solute. EnvZ. Receptor The EnvZ membrane protein changes shape in response to the high solute concentration,

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Figure 15.2 A Model Signal Transduction Pathway

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  1. Figure 15.2 A Model Signal Transduction Pathway Outer membrane of bacterium Cell wall Intermembrane space Plasma membrane Pores Environment Solute EnvZ Receptor The EnvZ membrane protein changes shape in response to the high solute concentration, catalyzing the addition of a phosphate from ATP. Signal Solutes enter the space between the two membranes through large pores in the outer membrane of E. coli. …and the phosphorylated OmpR changes shape, enabling it to bind to DNA and stimulate transcription of the ompC gene. OmpR Transduction The phosphate from EnvZ is transferred to the OmpR protein… DNA ompC mRNA OmpC protein inserts into the outer membrane, preventing solute entry and keeping the cell’s exterior osmotically balanced. OmpC protein

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