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Warning!. The video and narration in this presentation concerns the Female Reproductive System and uses explicit graphics and terminology dealing with this subject matter. Some material may not be suitable for younger viewers. Marieb’s Human Anatomy and Physiology Ninth Edition
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Warning! The video and narration in this presentation concerns the Female Reproductive System and uses explicit graphics and terminology dealing with this subject matter. Some material may not be suitable for younger viewers.
Marieb’s Human Anatomy and Physiology Ninth Edition Marieb w Hoehn Chapter 27 Female Reproductive System Lecture 19 Part 1: Overview; Ovaries/Ovarian Cycle
Functions of the Female Reproductive System • Produce and maintain sex cells (eggs) – a function of the ovaries, the primary sex organ • Transport eggs to site of fertilization • Produce female sex hormones • Provide favorable environment for development of offspring • Move offspring to outside (birth)
Organs of the Female Reproductive System (In anteflexion) (Skene’s glands; lesser vestibular glands) (Bartholin’s glands) Figure from: Martini, Anatomy & Physiology, Prentice Hall, 2001
Ovaries and Their Attachments Oophorectomy – removal of one or both ovaries Fold of peritoneum that attaches to sides and floor of pelvic cavity (limits side-to-side movement and rotation) Posterior view Figure from: Martini, Anatomy & Physiology, Prentice Hall, 2001
Overview of Female Reproductive Cycle Figure from: Hole’s Human A&P, 12th edition, 2010
Overview of the Ovarian Cycle Ovarian cycle – events occurring monthly in an ovary (oocyte growth and meiosis occur); cycle is usually about 28 days long Figure from: Hole’s Human A&P, 12th edition, 2010 Two phases: 1) Follicular phase 2) Luteal phase
Oogenesis Oogonia = stem cells Process stops in meiosis I (Prophase) Stimulated by FSH/LH About 2 million primary oocytes at birth. By puberty, there are about 400,000. Fewer than 400-500 will be released during a female’s reproductive life. Probably fewer than 10 will be fertilized. How does oogenesis differ from spermatogenesis? How is it the same?
Ovarian Cycle – Preovulatory (Follicular) Phase Figure from: Martini, Anatomy & Physiology, Prentice Hall, 2001 (Graafian) 1.5 cm Many Few One Thecal and granulosa cells produce estrogens 8-10 days after beginning of cycle 10-14 days (FSH) (FSH) LH Meiosis II started Meiosis I Estrogen
Ovarian Cycle – Postovulatory (Luteal) Phase (Day 14) 12 days post ovulation Lipids used to synthesize progestins, e.g., progesterone (prepares uterine lining for implantation) LH If fertilization has not occurred LH Figure from: Martini, Anatomy & Physiology, Prentice Hall, 2001
Ovulation Figure from: Hole’s Human A&P, 12th edition, 2010
Review of Ovarian Cycle • Preovulatory (follicular) phase (Day 1-14) • FSH stimulates primordial follicle to develop • Primary follicle secretes estrogen (from cooperation of granulosa and thecal cells) • Tertiary follicle is a mature (Graafian) follicle • Postovulatory (luteal) phase (Day 15-28) • LH stimulates rupture of tertiary follicle (ovulation) • Secondary oocyte is released (still in meiosis II) • Corpus luteum develops from remnants of follicle • Corpus luteum secretes progesterone which prepares the uterus for implantation • If pregnancy does not occur, corpus luteum involutes to become the corpus albicans (scar tissue) and menstruation will occur
Review • Function of the female reproductive system • Produce and maintain sex cells (eggs) – a function of the ovaries, the primary sex organ • Transport eggs to site of fertilization • Provide favorable environment for development of offspring • Move offspring to outside (birth) • Produce female sex hormones
Review • Several ligaments hold female reproductive structures in place • Broad ligament • Suspensory ligament • Ovarian ligament • Uterosacral ligament • Peritoneum-lined recesses in female • Rectouterine pouch – separates uterus from colon • Vesciouterine pouch – separates uterus from urinary bladder
Review • During oogenesis • Oogonia stop development in meiosis I (before birth) • Secondary oocytes, rather than mature gametes, are released monthly at ovulation • Ovarian cycle • Cycle is about 28 days long • Two main phases • Preovulatory (follicular) – 14 days • Postovulatory (luteal) – 14 days