1 / 1

HF-ACTION

HF-ACTION. No difference in mortality/hospitalizations between the two arms (HR 0.93, 95% CI 0.84-1.02, p = 0.13). On adjustment for other prognostic factors, was ↓ in exercise training arm (p = 0.03)

rigel-burris
Download Presentation

HF-ACTION

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. HF-ACTION No difference in mortality/hospitalizations between the two arms (HR 0.93, 95% CI 0.84-1.02, p = 0.13). On adjustment for other prognostic factors, was ↓ in exercise training arm (p = 0.03) CV mortality & CV hospitalizations (p = 0.14), 6-minute walk distance similar, but peak VO2 higher in the exercise training arm Serious side effects similar between two arms (p = 0.26) (p < 0.0001) Usual care (n = 1,172) Exercise training (n = 1,159) Trial design: Patients with symptomatic systolic CHF on optimal medical therapy were randomized to either exercise training or usual medical care. Clinical outcomes were compared at 3 years. Results 1.0 20 15 0.7 13 12 m 10 0.5 ml/min/kg 5 Conclusions 0.1 • Prescribed exercise training program in patients with systolic CHF safe and effective, when added on to optimal medical therapy • Strengthens current recommendations for exercise in CHF patients 0 0 Change in 6-minute walk distance Change in Peak VO2 O’Connor CM, et al. JAMA 2009;301:1439-50

More Related