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Access high-quality health evidence through systematic reviews, studies, and overviews in multiple languages. Find answers to your medical queries efficiently with user-friendly tools.
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A Multilingual, RelationalDatabase of HealthEvidence Gabriel Rada, Daniel Capurro, Daniel PerezEpistemonikos foundation
Episte…what? EPISTEMONIKOS(ΕΠΙΣΤΗΜΟΝΙΚΟΣ ) Whatisworthknowing
Whowe are Epistemonikos is a nonprofitorganizationbasedin Santiago, Chile Ourmissionis“tobringhighqualityinformationclosertohealthdecisionmaking”
Theproblem: informationoverload New oral anticoagulants in atrial fibrillation
Theproblemisyoudontknowthesecrets of PubMed ("Atrial Fibrillation"[Mesh] OR "Atrial Flutter"[Mesh] OR ((atrial OR auricular) AND (fibrillation* OR flutter*)) OR AF[Text Word]) AND ("Factor Xa/antagonists AND inhibitors"[Mesh] OR ((factor xa OR factors 10a OR fXa OR autoprothrombin c OR thrombokinase) AND inhibit[Text Word]) OR (activated AND (factor x OR factors 10) AND inhibitor*) OR xabans[Text Word] OR (antistasin OR apixaban OR betrixaban OR du 176b OR eribaxaban OR fondaparinux OR idraparinux OR otamixaban OR razaxaban OR rivaroxaban OR aygin OR ym 150 OR ym150 OR LY517717 OR darexaban OR edoxaban OR SSR126517E) OR ((dabigatran OR BIBR1048) OR ximelagatran OR AZD0837))
Oooops… ..butyou can search “systematicreviews” [bestevidence]
Muchbetter, ah? Yoy can startreading …see ya!
Wake up!!! Youhavetoreadthem, compare whichstudiestheyinclude ….and begthey are wellconducted, saythesamething and addressthesamestudies. Out of bed, sleepyhead!!! 8 systematicreviewsfor my question
Thechallenge: toseparatethewheatfromthechaff 23,000,000 records only in PubMed • 0,25% are systematicreviews
Ourgoal TO AGGREGATE ALL THE RELEVANT HEALTH EVIDENCE (FOR DECISION-MAKING) INTO A SINGLE DATABASE.
www.epistemonikos.org • Free • Released 1 yearago
Multilingual interface • Multilingualsearch • Translations of abstracts
Whatevidence? Systematicreviews Overviews of reviews High-qualitystructuredsummaries Primarystudiesincluded in systematicreviews
Systematicreviews (SR) at the centre • Theaverage SR takesabout 1-year of work • Werescuethateffortbystoringidentifiedstudies From: http://www.navigatingeffectivetreatments.org.au/understanding_systematic_reviews.html The Centre for Health Communication and Participation with support from the Australasian Cochrane Centre
Ifthereviewersfoundit, we’vegotit Unpublished!!!
Where do wesearch? 19 databases
How do wefeed Epistemonikos? • Combination of machine technology and humancollaboration
1 Automaticsearch and upload 2 Selection of actual systematicreviews by a network of collaborators 3 Extractionof thestudiesincluded in thesystematicreview
ADDED VALUE Notjust records RELATIONS ADDITIONAL DATA (metadata) RECORDS(Studies, reviews, overviews) TRANSLATIONS VISUALIZATION
Thenumbers • 158,211 records • 30,651 systematicreviews • Theworld’sbiggestcollection of certifiedsystematicreviews • 109,889 primarystudies • +200 collaborators
How Epistemonikos compares toexistingresources? Notjust records Other 16 databases ADDED VALUE RELATIONS ADDITIONAL DATA (metadata) Dare Cochrane TRANSLATIONS VISUALIZATION Epistemonikos Pubmed
Let’ seeanexample New oral anticoagulants in atrial fibrillation
Alltheevidence (systematicreviewsand studies) forourquestion*Thematrix of evidenceisexpectedtobereleased at theend of thisyear
Conclusions • One-stop shop forevidence • Multilingualdatabase • Userfriendly • Relationbetweenarticlesanswering a similar question • Visualisation of ‘alltheevidence’ for a specificquestion
Manythanks!!Contactus: contact@epistemonikos.org radagabriel@epistemonikos.org …orfollowus in yourpreferredlanguage: • English: @epistemonikos • Spanish: @epistemonikosEs • German: @epistemonikosDe • French: @epistemonikosFr • ….also in Facebook and google+ • Portuguese: @epistemonikosPt • Italian: @epistemonikosIt • Arabic: @epistemonikosAr • Dutch: @epistemonikosNl • Chinese: @epistemonikosZh