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Dive into the world of bioinformatics, where computers revolutionize biology. Learn about sequence analysis, evolutionary mapping, and modeling biological systems with algorithms like Needleman-Wunsch. Explore resources like UCSC Bioinformatics Website and NCBI for tools like BLAST and Genome Browser. Discover current research by experts like Vijay Pande and David Baker. Understand structural elucidation and information systems for drug testing. Utilize resources from Prof. Khuri's textbook and research papers for in-depth knowledge.
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Bioinformatics Stephen Voglewede
What is Bioinformatics • Computers have changed a lot of fields – including biology
Bioinformatics? • Sequence analysis • Evolutionary mapping • Modeling of biological systems
Algorithms and Tools • Needleman-Wunsch • UCSC Bioinformatics Website, NCBI • BLAST, Genome Browser
Current Research • Vijay Pande: Folding@home • David Baker: Foldit • Still looking for UCSC candidate • Areas of interest: structural elucidation, information systems for drug testing
What is your approach • Bioinformatics Textbook from Prof. Khuri’s class: pretty useful overview • Plenty of resources for Human Genome Project • Pour through research papers for Needleman-Wunsch and for current research – access issue might need to be addressed
What will be your final product? • Report containing the following: • Brief overview of history of bioinformatics • Description of some of the algorithms commonly used • Walkthrough of some of the tools available to for public use • Brief overview of some of the more interesting research in Bioinformatics right now