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Bioinformatics. Stephen Voglewede. What is Bioinformatics. Computers have changed a lot of fields – including biology. Bioinformatics?. Sequence analysis Evolutionary mapping Modeling of biological systems. Algorithms and Tools. Needleman-Wunsch UCSC Bioinformatics Website, NCBI
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Bioinformatics Stephen Voglewede
What is Bioinformatics • Computers have changed a lot of fields – including biology
Bioinformatics? • Sequence analysis • Evolutionary mapping • Modeling of biological systems
Algorithms and Tools • Needleman-Wunsch • UCSC Bioinformatics Website, NCBI • BLAST, Genome Browser
Current Research • Vijay Pande: Folding@home • David Baker: Foldit • Still looking for UCSC candidate • Areas of interest: structural elucidation, information systems for drug testing
What is your approach • Bioinformatics Textbook from Prof. Khuri’s class: pretty useful overview • Plenty of resources for Human Genome Project • Pour through research papers for Needleman-Wunsch and for current research – access issue might need to be addressed
What will be your final product? • Report containing the following: • Brief overview of history of bioinformatics • Description of some of the algorithms commonly used • Walkthrough of some of the tools available to for public use • Brief overview of some of the more interesting research in Bioinformatics right now