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DNA Nanotubes: Construction and Characterization of Filaments Composed of TX-tile Lattice

DNA Nanotubes: Construction and Characterization of Filaments Composed of TX-tile Lattice. Material: Triple-crossover (TAO) tiles modified with thiol-containing dsDNA stems projected out of the tile plane Analytical tools: TEM, AFM Key: Sticky-end  programmable (“smart glue”)

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DNA Nanotubes: Construction and Characterization of Filaments Composed of TX-tile Lattice

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  1. DNA Nanotubes: Construction and Characterization of Filaments Composed of TX-tile Lattice

  2. Material: Triple-crossover (TAO) tiles modified with thiol-containing dsDNA stems projected out of the tile plane • Analytical tools: TEM, AFM • Key: Sticky-end  programmable (“smart glue”) • Properly designed sets of DNA oligonucleotides are able to self-assemble into complex, highly organized structures. • Applications • Scaffolds for the creation for the creaction of nanoelectic circuits and other desired objects requiring nanometer scale feature resolution

  3. Interesting filamentous structures • The length scale of DNA nanotubes • Experimental results • 1. Reaction of thiolated DNA with nanogold • 2. Reaction of DNA containing free amine with Modified nanogold • 3. DNA nanotube formation via disulfide and polysulfide structures between tiles

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