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OBJECTIVES. To understand the purpose and indications for epidural lysis of adhesionsTo present evidence based literature for epidural lysis of adhesionsTo afford the pain practitioner the ability to incorporate epidural lysis procedures into a multidisciplinary pain treatment algorhythm. INTRODU
E N D
2. OBJECTIVES To understand the purpose and indications for epidural lysis of adhesions
To present evidence based literature for epidural lysis of adhesions
To afford the pain practitioner the ability to incorporate epidural lysis procedures into a multidisciplinary pain treatment algorhythm
Incidence
Pain is the most common reason patients present to their physicians.
LBP is the most common type of pain experienced by adults.
Second leading cause of work absence IN PATIENTS <50 YEARS OLD - first is common cold
Cost to society - billions $$ in:
missed days of work (employer)
poor job performance/productivity (employer)
medical care costs
disability programs (we all see numerous patients already on disablility secondary to NON-SPECIFIC LBP)
early retirement - therefore early Medicare consumerIncidence
Pain is the most common reason patients present to their physicians.
LBP is the most common type of pain experienced by adults.
Second leading cause of work absence IN PATIENTS <50 YEARS OLD - first is common cold
Cost to society - billions $$ in:
missed days of work (employer)
poor job performance/productivity (employer)
medical care costs
disability programs (we all see numerous patients already on disablility secondary to NON-SPECIFIC LBP)
early retirement - therefore early Medicare consumer
3. INTRODUCTION Lifetime prevalence of low back pain is 65 - 80%
Post laminectomy syndrome occurs in 5 - 40% of lumbar spine operations
13% of low back pain patients have significant disability
44 million U.S. households have at least one adult with chronic pain Stats from USA Today 8/9/01Stats from USA Today 8/9/01
4. DEFINITION OF EPIDURAL LYSIS
INDICATIONS
EVIDENCE REGARDING LYSIS
PROCEDURE PROTOCOL
MULTIDISCIPLINARY TREATMENT ALGORHYTHM INTRODUCTION
5. EPIDURAL LYSIS OF ADHESIONSNOMENCLATURE Epidural neuroplasty
Epidural neurolysis
Epidural lysis
Epidural adhesiolysis
Percutaneous adhesiolysis
Percutaneous epidural neuroplasty
Racz’s Procedure
6. EPIDURAL LYSIS OF ADHESIONSHistory and Development 1901 Epidural injection for chronic LBP
1909 Epidural injections cure sciatica
1921 Epidurography
1989 Epidural neuroplasty
7. EPIDURAL LYSIS OF ADHESIONSDEFINITION “The site specific delivery of medication where the pressure-volume effect of medication (in the right tissue plane) frees up the nerve root, reduces swelling and allows the return of mobility”
-Gabor Racz, MD, Personal Communication
8. EPIDURAL LYSIS OF ADHESIONSDEFINITION The disruption of scar tissue/fibrosis and freeing of spinal nerve roots in the epidural space to allow deposition of medication at the site of pathology and pain generation in order to improve function
Richard Epter, MD Personal Communication
9. EPIDURAL LYSIS OF ADHESIONSMECHANISM Hydraulic
Chemical
Mechanical
10. Epidural adhesions alone
do not cause pain!
11. SPINAL PAIN GENERATORS Nerve Root Dura – Radicular
Ventral Dura – Axial
Facet Joint – Axial
Sacroiliac Joint – Axial
Disc – Axial
Bone/Vertebral Periosteum – Axial
Muscle – Axial / Diffuse
Ligaments – PLL – Axial
Fascia - Axial
12. SPINAL PAIN GENERATORS PROPOSED ETIOLOGIES OF CHRONIC LOW BACK AND LOWER EXTREMITY PAIN Inflammation
Edema
Fibrosis
Vascular compromise / venous congestion
Biochemical influences
Post lumbar laminectomy syndrome Disc herniation
Spinal Stenosis
Neural compression
Mechanical pressure on PLL
Decreased/absent nutrients to spinal nerve root
Central sensitization
13. EPIDURAL LYSIS OF ADHESIONSMECHANISMS OF PAIN
Pain is produced by the movement of
swollen inflamed nerve roots
McCarron RF, et al, The Inflammatory Effect of the Nucleus Pulposis: A Possible Element in the Pathogenesis of Low Back Pain, Spine, 1987, 12: 760-764
14. EPIDURAL LYSIS OF ADHESIONSMECHANISMS OF PAIN Associated irritation via direct mechanical encasement of nerve roots within scar tissue
And/Or
Associated epidural venous engorgement with resultant nerve root edema
15. EPIDURAL LYSIS OF ADHESIONSMECHANISMS OF PAIN Scar tissue compounded pain associated with nerve root by fixing it in one position and thus increasing the susceptibility of the nerve root to tension or compression
Kuslich SD, et al, The Tissue Origin of Low Back Pain and Sciatica: A Report of Pain Response to Tissue Stimulation During Operations on the Lumbar Spine Using Local Anesthesia, Orth Clin N Amer, 1991, 22: 181-187
16. EPIDURAL FIBROSISDIAGNOSIS MRI
CT
MYELOGRAPHY
17. EPIDURAL FIBROSISDIAGNOSIS EPIDUROGRAPHY
First reported use 1921
To identify filling defects due to epidural fibrosis/scarring
18. EPIDURAL FIBROSISDIAGNOSIS Caudal epidurography was effective in correlating a filling defect with patient’s reported level of pain
Racz GB, et al, Lysis of Adhesions in the Epidural Space, Techniques of Neurolysis, 1989, pp 57-72
Manchikanti L, et al, Role of Epidurography in Caudal Neuroplasty, Pain Digest, 1998, 8: 277-281
19. EPIDURAL FIBROSISETIOLOGY Surgical
Non-Surgical
20. EPIDURAL FIBROSISSURGICAL ETIOLOGY “Nothing can heal like cold, hard steel.”
Anonymous Orthopedic Surgeon
21. EPIDURAL FIBROSISSURGICAL ETIOLOGY POSTLAMINECTOMY SYNDROME
incidence estimated at
5 to 40%
of lumbar spine operations
including laminectomy, fusion, microsurgery
(failure rates as high as 68%)
Wilkinson HA, The Role of Improper Surgery in the Etiology of the Failed Back Syndrome, The Failed Back Syndrome, 2nd Edition, 1992, pp 1-3
22. EPIDURAL FIBROSISSURGICAL ETIOLOGY Probability of recurrent pain increases after lumbar discectomy as peridural scarring increases
Extensive scarring resulted in 3.2 times incidence of recurrent radicular pain
Ross J, et al, Association Between Peridural Scar and Recurrent Radicular Pain After Lumbar Discectomy: Magnetic Resonance Evaluation, Neurosurgery, 1996, 38: 855-863
23. EPIDURAL FIBROSISNON-SURGICAL ETIOLOGY Annular tear
Hematoma
Infection
Intrathecal Contrast
24. EPIDURAL FIBROSISEVIDENCE HIGH LEVELS OF INFLAMMATORY PHOSPHOLIPASE A2 IN LUMBAR DISC HERNIAITONS
Spine 1990 15; 674-678
Saal, JS
THE ROLE OF INFLAMMATION IN LUMBAR PAIN
Spine 1995 Aug 15;20(16):1821-7
Saal, JS
PHOSPHLIPASE A2 = INFLAMMATION IN THIS STUDY FROM “SPINE“ PUBLISHED IN AUGUST 1995:
EVIDENCE SUPPORTING INFLAMMATION AS A MAJOR CAUSE OF LOW BACK PAIN WAS PRESENTED.
AS HIGH LEVELS OF PHOSPHOLIPASE A2 ARE PRESENT IN DEGENERATIVE AND HERNIATED DISKS, AND THIS INFLAMMATORY ENZYME HAS BEEN SHOWN TO PRODUCE PERINEURAL INFLAMMATION AND CONDUCTION BLOCK, IT SEEMS THAT THE CLINICAL FEATURES OF MANY LBP PATIENTS MAY BE EXPLAINED BY BIOCHEMICAL FACTORS ALONE OR IN COMBINATION WITH MECHANICAL DEFORMATION OF LUMBAR TISSUES, RATHER THAN MECHANICAL FACTORS ALONE.
WHAT THIS SAYS IS - THAT WE NOW HAVE EVIDENCE FOR AN INFLAMMATORY ETIOLOGY OF LBP. IT IS BELIEVED THAT THIS INFLAMMATORY PROCESS MAY OCCUR IN CASES OF BULGING DISKS, HERNIATED DISKS AND INTERNAL DISK DISRUPTION WHERE NO OBVIOUS STRUCTURAL ABNORMALITY OF THE DISK EXISTS. AND THIS PROCESS CAN OCCUR ON A CHRONIC BASIS.
I ALSO BELIEVE THIS IS WHY EPIDURAL STEROIDS WORK FOR MANY PATIENTS. [==GO TO NEXT SLIDE]IN THIS STUDY FROM “SPINE“ PUBLISHED IN AUGUST 1995:
EVIDENCE SUPPORTING INFLAMMATION AS A MAJOR CAUSE OF LOW BACK PAIN WAS PRESENTED.
AS HIGH LEVELS OF PHOSPHOLIPASE A2 ARE PRESENT IN DEGENERATIVE AND HERNIATED DISKS, AND THIS INFLAMMATORY ENZYME HAS BEEN SHOWN TO PRODUCE PERINEURAL INFLAMMATION AND CONDUCTION BLOCK, IT SEEMS THAT THE CLINICAL FEATURES OF MANY LBP PATIENTS MAY BE EXPLAINED BY BIOCHEMICAL FACTORS ALONE OR IN COMBINATION WITH MECHANICAL DEFORMATION OF LUMBAR TISSUES, RATHER THAN MECHANICAL FACTORS ALONE.
WHAT THIS SAYS IS - THAT WE NOW HAVE EVIDENCE FOR AN INFLAMMATORY ETIOLOGY OF LBP. IT IS BELIEVED THAT THIS INFLAMMATORY PROCESS MAY OCCUR IN CASES OF BULGING DISKS, HERNIATED DISKS AND INTERNAL DISK DISRUPTION WHERE NO OBVIOUS STRUCTURAL ABNORMALITY OF THE DISK EXISTS. AND THIS PROCESS CAN OCCUR ON A CHRONIC BASIS.
I ALSO BELIEVE THIS IS WHY EPIDURAL STEROIDS WORK FOR MANY PATIENTS. [==GO TO NEXT SLIDE]
25. INFLAMMATORY SUBSTANCES LEAKING OUT OF INTERVERTEBRAL DISC
26. EPIDURAL FIBROSISEVIDENCE Injected homogenized nucleus pulposis results in inflammation of (dog)
spinal cord segments
McCarron RF, Epidural Fibrosis: Experimental Model and Therapeutic Alternatives; Techniques of Neurolysis, 1989, 87-94
27. EPIDURAL FIBROSISEVIDENCE
McCarron RF, Epidural Fibrosis: Experimental Model and Therapeutic Alternatives; Techniques of Neurolysis, 1989, 87-94
Courtesy of G Racz, MD
28. EPIDURAL FIBROSISEvidence Periradicular fibrosis and vascular abnormalities occur with herniated discs
Cooper, et al, Herniated Intervertebral Disc Associated Abnormalities without Inflammatory Cell Infiltration, Spine, 1995, 20: 591-598
29. EPIDURAL FIBROSISEvidence Pathological changes including perineural / intraneural fibrosis, nerve root edema, focal demyelination occur in and around the nerve root complex
Hoyland, et al, Intervertebral Foramen Venous Obstruction, Spine, 1989, 14: 558-568
30. EPIDURAL LYSIS OF ADHESIONSEFFICACY
31. INTERVENTIONAL MANAGEMENT EPIDURAL STEROIDS
Safety
Efficacy
Technique
Translaminar, Transforaminal…Transsacral
Cervical, Thoracic, Lumbar, Caudal
Volume
Medications
Catheter
Not all epidural steroid injections are alike!Not all epidural steroid injections are alike!
32. EPIDURAL STEROIDS Pasquier NM, et al. Injection-intra-et extraudrales de cocaine a dose minime daus le traitment de la sciatique. Bull Gen Ther 1901; 142: 196
Caussade G, et al. Traitement de al neuralgia sciatique par la methode de Sicard. Bull Soc Med Hosp Paris, 1909; 28: 865
Green PWB, et al. The role of epidural cortisone injection in the treatment of diskogenic low back pain. Clin Orthop 1980; 153: 121-125
Benzon HT. Epidural steroid injections for low back pain and lumbosacral radiculopathy. Pain 1986; 24:277-295
Bogduk N. Epidural steroids. Spine 1995; 20: 845-888
Carette S, et al. Epidural corticosteroid injections for sciatica due to herniated nucleus pulposis. N Engl J Med 1997; 336: 1634-1640
Not all epidural steroid injections are alike!Not all epidural steroid injections are alike!
33. EPIDURAL STEROIDS EFFICACY
Transforaminal > Caudal > Interlaminar
Comparison of Three Routes of Epidural Steroid Injections in Low Back Pain, Manchikanti L, et al, Pain Digest, 1999,
9: 277-285 Not all epidural steroid injections are alike!Not all epidural steroid injections are alike!
34. CAUDAL ESI
35. EPIDURAL STEROIDS EFFICACY Presence or absence of epidural ligaments or scarring may prevent migration of posteriorly administered injectate to the anterior epidural space
Weinstein SM, et al, Spine, 1995, 20: 1842-1846 Not all epidural steroid injections are alike!Not all epidural steroid injections are alike!
36. EPIDURAL STEROIDS EFFICACY
Foraminal approach provides good ventral flow
vs.
Interlaminar approach predominately dorsal flow, more removed from site of inflammation
Andrade A, et al, The Distribution of Radiologic Contrast Media by Lumbar Translaminar and Selective Neural Canals, Annual ISIS Meeting, Keystone, Colorado, January 1992
Not all epidural steroid injections are alike!Not all epidural steroid injections are alike!
37. INTERLAMINAR ESI
38. TRANSFORAMINAL ESI
39. EPIDURAL LYSIS OF ADHESIONSEFFICACY Percutaneous Epidural Neuroplasty: Prospective Evaluation of 0.9% NaCl Versus 10% NaCl With or Without Hyaluronidase
Heavner, et al, Regional Anesthesia and Pain Medicine, 1999, 24, 3: 202-207
40. EPIDURAL LYSIS OF ADHESIONSEFFICACY PURPOSE:
To determine if hypertonic saline or hyaluronidase influence treatment outcomes
Heavner, et al, Regional Anesthesia and Pain Medicine, 1999, 24, 3: 202-207
41. EPIDURAL LYSIS OF ADHESIONSEFFICACY
DESIGN: prospective, randomized
N=83 patients
(24 patients did not complete the study)
Criteria: Unilateral radiating pain distal to knee and low back pain
Results evaluated at 1, 3, 6 and 12 months
Heavner, et al, Regional Anesthesia and Pain Medicine, 1999, 24, 3: 202-207
42. EPIDURAL LYSIS OF ADHESIONSEFFICACY DESIGN:
GROUP A: hyaluronidase + hypertonic saline
GROUP B: hypertonic saline
GROUP C: isotonic saline
GROUP D: hyaluronidase + isotonic saline
Heavner, et al, Regional Anesthesia and Pain Medicine, 1999, 24, 3: 202-207
43. EPIDURAL LYSIS OF ADHESIONSEFFICACY RESULTS:
All groups obtained immediate relief after treatment
Max VAS scores improved in at least 25% of patients in all treatment groups at all follow up intervals
Both hypertonic saline groups were less likely to require other treatments vs. normal saline groups
Heavner, et al, Regional Anesthesia and Pain Medicine, 1999, 24, 3: 202-207
44. EPIDURAL LYSIS OF ADHESIONSEFFICACY CONCLUSION:
The results:
confirm the benefits of percutaneous epidural neuroplasty as part of an overall pain management strategy and the safety of the procedure
hyaluronidase does not change the outcome
less patients given hypertonic saline require additional treatments vs. patients given normal saline
Heavner, et al, Regional Anesthesia and Pain Medicine, 1999, 24, 3: 202-207
45. EPIDURAL LYSIS OF ADHESIONSEFFICACY Role of Adhesiolysis and Hypertonic Saline Neurolysis in Management of Low Back Pain: Evaluation of Modification of the Racz Protocol
Manchikanti L, et al, Pain Digest, 1999; 9: 91-96
46. EPIDURAL LYSIS OF ADHESIONSEFFICACY PURPOSE:
To compare 3 day vs. 1 or 2 day lysis procedures for efficacy and to evaluate cost effectiveness of lysis and hypertonic saline in management of chronic low back pain
Manchikanti L, et al, Role of Adhesiolysis and Hypertonic Saline Neurolysis,
Pain Digest, 1999; 9: 91-96
47. EPIDURAL LYSIS OF ADHESIONSEFFICACY Modified Racz Protocol:
3 Days ? 1 or 2 Days
Bupivacaine ? Lidocaine
Triamcinolone ? Betamethasone
Decreased Volume
Manchikanti L, et al, Role of Adhesiolysis and Hypertonic Saline Neurolysis,
Pain Digest, 1999; 9: 91-96
48. EPIDURAL LYSIS OF ADHESIONSEFFICACY CONCLUSION:
Modified adhesiolysis is safe and cost-effective technique for relieving chronic intractable pain
Repeat or multiple procedures provided significant relief with increasing duration with each procedure in a staircase fashion
There was no significant difference between 1, 2 or 3 day adhesiolysis
Manchikanti L, et al, Role of Adhesiolysis and Hypertonic Saline Neurolysis,
Pain Digest, 1999; 9: 91-96
49. EPIDURAL LYSIS OF ADHESIONSEFFICACY Role of One Day Adhesiolysis in Management of Chronic Low Back Pain:
A Randomized Clinical Trial
Manchikanti L, et al, Pain Physician, 2001;4:153-166
50. EPIDURAL LYSIS OF ADHESIONSEFFICACY DESIGN: randomized, double blind, controlled
N=45 patients
2 groups of 15 and 30 patients each
GROUP 1: CONTROLS = meds + PT + exercise
GROUP 2: cath + adhesiolysis + hypertonic saline neurolysis
Manchikanti L, et al, Pain Physician, 2001;4:153-166
51. EPIDURAL LYSIS OF ADHESIONSEFFICACY RESULTS:
GROUP 2 (WITH ADHESIOLYIS/10% SALINE) had statistically significant improvement in pain, physical health, mental health, functional status, psychological status and narcotic intake
Manchikanti L, et al, Pain Physician, 2001;4:153-166
52. EPIDURAL LYSIS OF ADHESIONSEFFICACY RESULTS:
GROUP 2 (WITH ADHESIOLYIS/10% Saline) had significant relief (>50% with 1-3 injections)
3 months: 97%
6 months: 93%
12 months: 47%
Manchikanti L, et al, Pain Physician, 2001;4:153-166
53. EPIDURAL LYSIS OF ADHESIONSEFFICACY CONCLUSIONS:
Epidural adhesiolysis with hypertonic saline performed on a one day basis is an effective treatment for chronic low back pain patients (without facet pain) that failed
fluoroscopically directed epidural steroid injections
Manchikanti L, et al, Pain Physician, 2001;4:153-166
54. EPIDURAL LYSIS OF ADHESIONSEFFICACY One Day Adhesiolysis and Hypertonic Saline Neurolysis in Treatment of Chronic Low Back Pain: A Randomized, Double-Blind Trial
Manchikanti L, et al, Pain Physician, 2004;7:177-186
55. EPIDURAL LYSIS OF ADHESIONSEFFICACY DESIGN: randomized, double blind, controlled
N=75 patients
3 groups of 25 patients each
GROUP 1: CONTROLS = cath + no adhesiolysis + LA + NSS + steroid
GROUP 2: cath + adhesiolysis +LA + NSS + steroid
GROUP 3: cath + adhesiolysis + LA + 10% saline + steroid
Manchikanti L, et al, Pain Physician, 2004;7:177-186
56. EPIDURAL LYSIS OF ADHESIONSEFFICACY RESULTS:
GROUPS 2 & 3 (WITH ADHESIOLYIS) had statistically significant improvement vs. baseline and GROUP 1
at 3, 6 and 12 months
Manchikanti L, et al, Pain Physician, 2004;7:177-186
58. EPIDURAL LYSIS OF ADHESIONSEFFICACY RESULTS:
GROUPS 2 & 3 (WITH ADHESIOLYIS) at 6 & 12 months
had statistically significant pain relief
GROUP 2: 60%
GROUP 3: 72%
vs
GROUP 1: 0%
Manchikanti L, et al, Pain Physician, 2004;7:177-186
59. EPIDURAL LYSIS OF ADHESIONSEFFICACY RESULTS:
GROUPS 2 & 3 (WITH ADHESIOLYIS) had statistically significant differences in
pain relief, Oswestry Disability Index and range of motion
Manchikanti L, et al, Pain Physician, 2004;7:177-186
61. EPIDURAL LYSIS OF ADHESIONSEFFICACY CONCLUSIONS:
Percutaneous adhesiolysis (+/- hypertonic saline) is a safe and
effective treatment for chronic refractory
low back and lower extremity pain
Manchikanti L, et al, Pain Physician, 2004;7:177-186
62. EPIDURAL LYSIS OF ADHESIONSEFFICACY Hyaluronidase added
N=100
82% initial pain relief (vs. 68% w/o hyaluronidase)
No significant long term improvement (14% vs. 12%)
Arthur J, Lysis of Epidural Adhesions in the Treatment of Chronic Back Pain
63. EPIDURAL LYSIS OF ADHESIONSEFFICACY Hyaluronidase reduced the neuroplasty treatment failure rate from 18% to 6%
Racz G, et al, Lysis of Epidural Adhesions, Waldman, Interventional Pain Management, 1996, 339-351
64. EPIDURAL LYSIS OF ADHESIONSPROCEDURE
65. EPIDURAL LYSIS OF ADHESIONSINDICATIONS Epidural Scarring / Fibrosis
Failed Back/Neck Surgery Syndrome
Disc Disruption
Spinal Stenosis
Vertebral Compression Fractures
Multilevel Degenerative Arthritis
66. TECHNICAL CONCEPTS AWAKE PATIENT
Sterile Technique
Fluoroscopic Guidance
Fluoroscopic Anatomy
3-D Relationships
Biplanar Fluoroscopy
Water Soluble Dye
Real-time Fluoroscopy Tunnel Vision
Curved/Blunt Needles
Small Bore Extension
Miscellaneous:
Read Labels
Consistent Routine
Same Personnel
67. PROCEDURE Obtain informed consent
NPO
Appropriate monitoring
+/ - Sedation
68. PROCEDURELESION SPECIFICITY Know your target point based on patient’s history, physical exam, pain/dermatomal pattern
71. LUMBAR ANATOMY
72. TECHNIQUEPOSITIONING & APPROACH
73. PROCEDUREPOSITIONING Prone (vs lateral decubitus)
Pillows beneath abdomen/pelvis, shins
Arms comfortable, abducted less than 90 degrees
74. PROCEDURETECHNIQUE Meticulous attention to sterile technique
Sterile prep/drape – gluteal fold gauze
Exact midline AP fluro
SQ Local anesthetic (bupivacaine 0.25% / ropivacaine 0.2%) infiltration with 25/27g needle
Skin nick with 18g needle
75. TECHNIQUECAUDAL ACCESS
76. TECHNIQUECAUDAL ACCESS
77. PROCEDURETECHNIQUE Epidural Access:
15g or 16g RX Coudé® or Straight
16g R.K.™ Straight
18g RX Coudé® or Straight(21g Versakath only)
SCA
FIC
78. EQUIPMENT
79. PROCEDURETECHNIQUE Insert needle via sacral hiatus (2 cm lateral and inferior) not above S3 foramina
Aspirate and then inject 10 ml iohexol 240 (Omnipaque); observe initial few mls in lateral view to confirm cephalad spread and rule out vascular, subdural / subarachnoid injection
Identify and document filling defect
80. TECHNIQUECAUDAL ACCESS
81. TECHNIQUECAUDAL ACCESS
82. TECHNIQUECAUDAL ACCESS
83. TECHNIQUECAUDAL ACCESS
84. TECHNIQUECAUDAL ACCESS
85. TECHNIQUECAUDAL ACCESS
86. TECHNIQUECAUDAL ACCESS
87. TECHNIQUECAUDAL ACCESS
88. TECHNIQUECAUDAL ACCESS
89. LYSIS OF ADHESIONS
90. PROCEDURETECHNIQUE Rotate bevel needle 135 degrees ventrolateral to desired side
Place 15 degree bend in catheter tip
Advance spring tip catheter to desired lesion site – warn patient of possible paresthesias
Confirm ventrolateral catheter placement in AP and lateral views
Remove stylet and needle
Place connector on catheter
91. PROCEDURETECHNIQUE Must document runoff –
up and down epidural space
and/or
out foramen
92. PROCEDURETECHNIQUE Aspirate catheter and inject an additional 3 – 5 (up to 10) ml of iohexol
Check lower extremity motor function
Rule out loculation, vascular, subdural / subarachnoid injection
Aspirate and inject hyaluronidase 1500u
Aspirate and inject an additional 2 ml of iohexol
93. LYSIS OF ADHESIONS
94. LYSIS OF ADHESIONS
95. LYSIS OF ADHESIONS
96. LYSIS OF ADHESIONS
97. PROCEDURETECHNIQUE Visualize and document dye spread into area of previous filling defect and outline the targeted nerve root
Aspirate and inject preservative free ropivacaine / bupivacaine and triamcinolone / decadron
Secure catheter and place 0.2 micron filter
Observe for 30 minutes to rule out subarachnoid / subdural injection
**Aspirate and inject ropivacaine / bupivacaine
Begin preservative free 10% saline infusion
98. LYSIS OF ADHESIONS
99. PROCEDURETECHNIQUE
100. PROCEDURETECHNIQUE ONE DAY
Flush catheter with 1.5 ml preservative free saline
Discontinue catheter
Apply triple antibiotic ointment
Apply dressing / band aid
Provide discharge instructions
Follow up
101. PROCEDURETECHNIQUE TWO OR THREE DAY
Aspirate catheter and inject local anesthetic
Wait 15 minutes and begin 6-10 ml 10% saline infusion over 20-30 minutes
Flush catheter with 1.5 ml preservative free saline
Discontinue catheter
102. PROCEDURETECHNIQUE TWO OR THREE DAY
Apply triple antibiotic ointment
Apply dressing / band aid
Provide discharge instructions
Follow up
103. CERVICAL ESI
104. CERVICAL LOA
105. CERVICAL LOA
106. EPIDURAL LYSIS OF ADHESIONSPOTENTIAL COMPLICATIONS Bleeding
Nerve injury
Spinal cord ischemia / paralysis
Infection
Allergic reactions
Subdural/subarachnoid injection
Bowel/bladder dysfunction
Cardiac arrhythmias
Perineal numbness (up to 1 month)
Catheter shearing
107. COMPLICATIONSSUBDURAL
108. MULTIDISCIPLINARY TREATMENT
109. MULTIDISCIPLINARY TREATMENT PHILOSOPHY GOAL = FUNCTIONAL RESTORATION
Early vs. Late Treatment
Make a DIAGNOSIS
Algorhythm
Conservative
Do No Harm!! EARLY VS LATE: Preemptive Analgesia
Tachyphylaxis (Local Anesthetics)
Prevention of Neuropathic Pain, Central
Sensitization/Windup Phenomenon, chasing with
more and more=behind the 8 ball
ALGORHYTHM: Systematic Approach for Evaluation & Management
CONSERVATIVE: Always begin with the least risky option
DO NO HARM: What we learned in Med School
REFERRAL: This is the big question!! As physicians we should all do
what is REASONABLE. Determine your level of comfort
with treatment and then REFER when appropriate based
on your best judgement.EARLY VS LATE: Preemptive Analgesia
Tachyphylaxis (Local Anesthetics)
Prevention of Neuropathic Pain, Central
Sensitization/Windup Phenomenon, chasing with
more and more=behind the 8 ball
ALGORHYTHM: Systematic Approach for Evaluation & Management
CONSERVATIVE: Always begin with the least risky option
DO NO HARM: What we learned in Med School
REFERRAL: This is the big question!! As physicians we should all do
what is REASONABLE. Determine your level of comfort
with treatment and then REFER when appropriate based
on your best judgement.
110. MULTIDISCIPLINARY TREATMENT PHILOSOPHY
111. MULTIDISCIPLINARY TREATMENT PHILOSOPHY EARLY VS LATE: Preemptive Analgesia
Tachyphylaxis (Local Anesthetics)
Prevention of Neuropathic Pain, Central
Sensitization/Windup Phenomenon, chasing with
more and more=behind the 8 ball
ALGORHYTHM: Systematic Approach for Evaluation & Management
CONSERVATIVE: Always begin with the least risky option
DO NO HARM: What we learned in Med School
REFERRAL: This is the big question!! As physicians we should all do
what is REASONABLE. Determine your level of comfort
with treatment and then REFER when appropriate based
on your best judgement.EARLY VS LATE: Preemptive Analgesia
Tachyphylaxis (Local Anesthetics)
Prevention of Neuropathic Pain, Central
Sensitization/Windup Phenomenon, chasing with
more and more=behind the 8 ball
ALGORHYTHM: Systematic Approach for Evaluation & Management
CONSERVATIVE: Always begin with the least risky option
DO NO HARM: What we learned in Med School
REFERRAL: This is the big question!! As physicians we should all do
what is REASONABLE. Determine your level of comfort
with treatment and then REFER when appropriate based
on your best judgement.
112. MULTIDISCIPLINARY TREATMENT PHILOSOPHY EARLY VS LATE: Preemptive Analgesia
Tachyphylaxis (Local Anesthetics)
Prevention of Neuropathic Pain, Central
Sensitization/Windup Phenomenon, chasing with
more and more=behind the 8 ball
ALGORHYTHM: Systematic Approach for Evaluation & Management
CONSERVATIVE: Always begin with the least risky option
DO NO HARM: What we learned in Med School
REFERRAL: This is the big question!! As physicians we should all do
what is REASONABLE. Determine your level of comfort
with treatment and then REFER when appropriate based
on your best judgement.EARLY VS LATE: Preemptive Analgesia
Tachyphylaxis (Local Anesthetics)
Prevention of Neuropathic Pain, Central
Sensitization/Windup Phenomenon, chasing with
more and more=behind the 8 ball
ALGORHYTHM: Systematic Approach for Evaluation & Management
CONSERVATIVE: Always begin with the least risky option
DO NO HARM: What we learned in Med School
REFERRAL: This is the big question!! As physicians we should all do
what is REASONABLE. Determine your level of comfort
with treatment and then REFER when appropriate based
on your best judgement.
113. MULTIDISCIPLINARY TREATMENT PHILOSOPHY NERVE BLOCKS /
INTERVENTIONS
ADVANTAGES: Facilitate PT/Activity
Specific Pain Relief
Demonstrates Compliance
Low Risk
Lower Cost, Risk, Side Effects vs. Surgery
Reduce Medications
Outpatient Procedure NERVE BLOCKS PROVIDE SIGNIFICANTLY MORE SPECIFIC RELIEF THAN ANY OTHER MODALITY - ATLEAST FOR A PERIOD OF TIME. I SEE MANY PATIENTS WHO WERE UNABLE TO TOLERATE A PT REGIMEN WITHOUT NERVE BLOCKS BUT WITH THEM ACHIEVE PROGRESS. THOSE WHERE NO BENEFIT OCCURS ARE OFTEN PATIENTS WITH SIGNIFICANT ISSUES REGARDING SECONDARY GAIN AND LITTLE MOTIVATION TO IMPROVE.
THE MOST SINGLE IMPORTANT ADVANTAGE OF NERVE BLOCKS IS THAT THEY FACILITATE PT.
ACCEPTANCE OF NERVE BLOCKS AS A PART OF THE PAIN MANAGEMENT REGIMEN DEMONSTRATES COMPLIANCE. WE ALL KNOW THE PATIENT WHO IS TOO SCARED TO HAVE A NERVE BLOCK BECAUSE THEY ARE AFRAID OF NEEDLES BUT REPORT A PAIN SCORE OF 10. THIS SEEMS TO BE MORE COMMON IN THE WC POPULATION - ATLEAST IN MY PRACTICE.
THESE ARE LOW RISK PROCEDURES IN THE HANDS OF A SKILLED ANESTHESIOLOGIST.
LOWER COST, RISK AND POTENTIAL SIDE EFFECTS VS. SURGERY.
NERVE BLOCKS HELP REDUCE THE NEED FOR MEDICATIONS OR ALLOW THOSE USED TO BE MORE BENEFICIAL - LOWERS THRESHOLD.
MOST BLOCKS ARE DONE ON AN OUTPATIENT BASIS. NERVE BLOCKS PROVIDE SIGNIFICANTLY MORE SPECIFIC RELIEF THAN ANY OTHER MODALITY - ATLEAST FOR A PERIOD OF TIME. I SEE MANY PATIENTS WHO WERE UNABLE TO TOLERATE A PT REGIMEN WITHOUT NERVE BLOCKS BUT WITH THEM ACHIEVE PROGRESS. THOSE WHERE NO BENEFIT OCCURS ARE OFTEN PATIENTS WITH SIGNIFICANT ISSUES REGARDING SECONDARY GAIN AND LITTLE MOTIVATION TO IMPROVE.
THE MOST SINGLE IMPORTANT ADVANTAGE OF NERVE BLOCKS IS THAT THEY FACILITATE PT.
ACCEPTANCE OF NERVE BLOCKS AS A PART OF THE PAIN MANAGEMENT REGIMEN DEMONSTRATES COMPLIANCE. WE ALL KNOW THE PATIENT WHO IS TOO SCARED TO HAVE A NERVE BLOCK BECAUSE THEY ARE AFRAID OF NEEDLES BUT REPORT A PAIN SCORE OF 10. THIS SEEMS TO BE MORE COMMON IN THE WC POPULATION - ATLEAST IN MY PRACTICE.
THESE ARE LOW RISK PROCEDURES IN THE HANDS OF A SKILLED ANESTHESIOLOGIST.
LOWER COST, RISK AND POTENTIAL SIDE EFFECTS VS. SURGERY.
NERVE BLOCKS HELP REDUCE THE NEED FOR MEDICATIONS OR ALLOW THOSE USED TO BE MORE BENEFICIAL - LOWERS THRESHOLD.
MOST BLOCKS ARE DONE ON AN OUTPATIENT BASIS.
114. MULTIDISCIPLINARY TREATMENT PHILOSOPHY PHYSICAL THERAPY
Evaluation & Assessment
Passive Modalities
Passive Exercises
Active Exercises
Home Exercises
Wellness Program PASSIVE: Heat/Ice
Ultrasound
Electrical Stimualtion
Iontophoresis
TENS, MENS
PASSIVE: Heat/Ice
Ultrasound
Electrical Stimualtion
Iontophoresis
TENS, MENS
115. MULTIDISCIPLINARY TREATMENT PHILOSOPHY OUTCOME MEASURES:
ADLs
Quality of Life
Patient Satisfaction
Pain Character/Pattern
Pain Intensity / VAS
Pain Medication
Return to Work
116. CONCLUSION Epidural LOA is a reasonable, safe and cost effective pain management technique that can be utilized successfully, in properly selected patients, to treat a variety of chronic pain conditions I HOPE THAT FROM OUR DISCUSSION TODAY I HAVE BEEN ABLE TO PROVIDE YOU WITH AN (ENTHUSIASTIC) VIEW OF THE CAUSES OF LBP, THE EVALUATION OF LBP AND ITS MANAGEMENT.
AND LASTLY, I JUST WANT TO LEAVE YOU WITH THE FOLLOWING (THOUGHTS):I HOPE THAT FROM OUR DISCUSSION TODAY I HAVE BEEN ABLE TO PROVIDE YOU WITH AN (ENTHUSIASTIC) VIEW OF THE CAUSES OF LBP, THE EVALUATION OF LBP AND ITS MANAGEMENT.
AND LASTLY, I JUST WANT TO LEAVE YOU WITH THE FOLLOWING (THOUGHTS):