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Training Initiative in Thrombocytopenia, Anaemia and Neutropenia Introduction. Training Initiative in Thrombocytopenia, Anaemia and Neutropenia A collaborative project of the European Oncology Nursing Society and European Society for Blood and Marrow Transplantation.
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Training Initiative in Thrombocytopenia, Anaemia and NeutropeniaIntroduction
Training Initiative in Thrombocytopenia, Anaemia and Neutropenia A collaborative project of the European Oncology Nursing Society and European Society for Blood and Marrow Transplantation
History of TITAN 2018 update Training initiative developed by EONS 2008 Previous TITAN courses have been translated into 13 languages Nurses from 25 countries have participated 2008-2016
TITAN provides an opportunity Improve the prevention, detection and management of haematological toxicities in patients with cancer Give nurses greater knowledge to assess, manage and educate patients with haematological toxicities High quality patient care and improved patient outcomes
Learning objectives • Describe different types of blood cells, including their functions and normal development and lifespan • Define normal and abnormal blood values and their consequences • Define haematological toxicities • Consider aspects for effective patient education of haematological toxicities
Interactive course • Course structure • presentations of core subject areas • multiple choice questions for each section • supporting activities and case studies • Course designed to be interactive • freedom to ask questions throughout the day • ‘networking’ opportunities during intervals • Course evaluation is important • please complete and return your forms throughout the day as we go through the different parts of the course
TITAN – an essential topic Negative impact on patient outcomes Cancer treatments Dose intensity Myelosuppression Haematological toxicities Acute life-threatening consequences
Why do these toxicities matter?1. Impact on dose intensity total dose delivered time to complete therapy Dose intensity = Reducing the dose delivered, or the time to complete therapy, impacts on the relative dose intensity (RDI) Low RDI increases risk of poorer treatment outcomes
Why do these toxicities matter?2. Impact of age Age-related pharmacokinetic changes increase cancer-treatment toxicities Age-related decline in pluripotent haematopoietic stem cell reserve delays recovery of blood counts Elderly patients may be under-treated because of concerns regarding toxicities Elderly patients would benefit from proactive haematopoietic support to optimise treatment
Potential life-threatening consequences Neutropenia Anaemia Thrombocytopenia Risk of infection and Febrile Neutropenia Impact on Quality of life Risk of bleeding and haemorrhage
Essential role of the nurse • Assessing and identifying high risk patients • Contributing to pro-active management strategies • Making patients and their families aware of the implications and impact of haematological toxicities • Educating patients and their families about prevention and early detection strategies • symptoms often appear in the home environment
Evidence base Risk assessment models: identify and validate risk factors Impact of myelosuppression on vulnerability to infection Underpins clinical guidelines: establish trigger values and targets for interventions Clinical practice Use assessment to select patients most vulnerable to myelosuppression Educate patients about haematological toxicities Monitor patient blood counts and symptoms over time, know when to intervene Importance of evidence-based clinical practice
TITAN – an essential topic Negative impact on patient outcomes Cancer treatments Dose intensity Myelosuppression Haematological toxicities Acute life-threatening consequences Neutropenia Anaemia Thrombocytopenia
Training Initiative in Thrombocytopenia, Anaemia and Neutropenia