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MISTAKES IN MEIOSIS. Beth Walker CP Biology. Nondisjunction. failure of homologous chromosomes to separate correctly during anaphase I or II of meiosis. Nondisjunction can lead to…. Makes gametes with one extra OR one less chromosome. monosomy. Monosomy has 1 less chromosome
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MISTAKES IN MEIOSIS Beth Walker CP Biology
Nondisjunction • failure of homologous chromosomes to separate correctly during anaphase I or II of meiosis.
Nondisjunction can lead to…. • Makes gametes with one extra OR one less chromosome
monosomy • Monosomy has 1 less chromosome Ex. sperm (22) + egg (23) = baby (45)
trisomy • Trisomy has 1 extra chromosome Ex. sperm (23) + egg (24) = baby (47)
Example of monosomy • Turner’s Syndrome 45 chromosomes *Mother only gives 22 chromosomes *Father gives 23 chromosomes
EXAMPLE OF TRISOMY • Down’s Syndrome extra chromosome #21
Example of trisomy • Klinefelter’s Syndrome extra sex chromosome (#23)
Polyploidy • When none of the homologous chromosomes separate the gamete stays diploid(2n) instead of separating and becoming haploid(n) • Ex. 2n gamete + n gamete = 3n baby (triploid) (abnormal) (normal) 2n gamete + 2n gamete = 4n baby (tetraploid)
Polyploidy at work • Extra sets of chromosomes polyploidy • Polyploidy is common in plants, but rare in animals (usually leads to death of the zygote in animals)