1 / 34

MUSCLE STRUCTURE AND PHYSIOLOGY J. Rosenbluth, April 2012

MUSCLE STRUCTURE AND PHYSIOLOGY J. Rosenbluth, April 2012. MUSCLE. Skeletal muscle fibers Contraction mechanism Excitation-contraction coupling Gross properties of skeletal muscle Pathology/Clinical examples. Myofibrils. Skeletal muscle band pattern.

sabin
Download Presentation

MUSCLE STRUCTURE AND PHYSIOLOGY J. Rosenbluth, April 2012

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. MUSCLE STRUCTURE AND PHYSIOLOGY J. Rosenbluth, April 2012

  2. MUSCLE • Skeletal muscle fibers • Contraction mechanism • Excitation-contraction coupling • Gross properties of skeletal muscle • Pathology/Clinical examples

  3. Myofibrils

  4. Skeletal muscle band pattern

  5. Double “antiparallel” array of myofilamnts (H.E.Huxley)

  6. Sliding filament model

  7. Myosin filament formation

  8. Low-angle X-ray diffraction of skeletal muscle (meridional pattern)

  9. Decorated F-actin

  10. Antiparallel array of myofilaments

  11. Double hexagonal array (vertebrate skeletal muscle)

  12. Crossbridge position during relaxation (top) vs contraction (bottom)

  13. Attached Released Cocked Force generating Attached Cross-bridge Cycle

  14. Triads (amphibian)

  15. Skeletal muscle triad (amphibian)

  16. Triad structure

  17. Actin filament with Tr and Tm

  18. Tropomyosin movement

  19. Pennate Muscles

  20. Length-Tension Relationship

  21. Load-Velocity Relationship

  22. Twitch vs Tetanic Tension

  23. Fiber types (cat gastrocnemius)

  24. Twitch contraction times

  25. Skeletal Muscle Fatigue

  26. “Winging”(facio-scapulo-humeral dystrophy)

  27. “Pseudohypertrophy” (Duchenne dystrophy)

  28. Charcot-Marie-Tooth disease

  29. Spinal muscular atrophy

More Related