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DEFINITIONS. DRUG DEPENDENCE - state when drug-taking becomes compulsive, taking precedence over other needs. Syn. substance dependenceDRUG ADDICTION - is not clearly defined but implies a physical dependence, however, sometimes it is used as a syn. to drug (substance) dependence DRUG ABUSE - more general term, includes recurrent use of any illegal/harmful substance, e.g., in sportTOLERANCE - the decrease in a pharmacological effect on repeated administration of the drugimply the need to i9460
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