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Dermatomes overlap. Skin. Peripheral nerve. Dorsal root. Ventral root. Dermatomes overlap. Skin. Peripheral nerve. Dorsal root. Ventral root. Dorsal column. Spinal cords. Dorsal root ganglion. Lateral column. “Anterolateral” column. Ventral column. Dorsal root. Spinal nerve.
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Dermatomesoverlap Skin Peripheral nerve Dorsal root Ventral root
Dermatomesoverlap Skin Peripheral nerve Dorsal root Ventral root
Dorsalcolumn Spinal cords Dorsal rootganglion Lateral column “Anterolateral” column Ventral column Dorsal root Spinalnerve Dorsal horn Intermediate zone Ventral horn Ventral root
Anterolateral system Dorsal column-medial lemniscal system Bare nerve ending Merkel’s receptor Meissner’s corpuscle Pacinian corpuscle Receptor projections to systems
LgTermPatterns Reminder: Rexed’s laminae
Demyelination Somatotopic organization of the dorsal columns DC lesion Rostral Caudal
Lg&SmTermPatterns Lamina 5
Lg&SmTermPatterns Lamina 5
Spinal Hemisection Ipsilateral loss of touch… Contralateral loss of pain… (2-3 segments caudal to injury) Mechanoreceptor Nociceptor
Syringomyelia Site of lesion • Bilateral loss of pain & thermal senses • Preservation of mechanosensations
Postcentralgyrus / Insular/Cingulatecortex Postcentralgyrus / 1° SScx Dorsalcolumnnuclei Internalarcuatefibers Pain,thermal,itch Mechano… Dorsalhorn Spinalcommissure Dorsal column-medial lemniscalsystem Anterolateralsystem Also: •Reticular formation •Superior colliculus (mesencephalon)
Medial dorsal Ventral posterior medial-VPM (trigem) Ventral posterior lateral-VPL (spinal) Touch Pain Ventral posterior (VMpo) Somatic Sensory Thalamus
Leg area Arm area Face area Internal capsule Ventral posterior nucleus