MOUSE DATA IN SWISS-PROT

1. MOUSE DATA IN SWISS-PROT • Michele Magrane, Vivien Junker, Stephanie Kappus, Fiona Lang, Nicoletta Mitaritonna, Claire O’Donovan, Rolf Apweiler. • EMBL Outstation - The European Bioinformatics Institute (EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, U.K. • SWISS-PROT • Curated, non-redundant protein sequence database. • Provides a high level of annotation and integration with other databases. • TrEMBL • Created due to the increasing amount of data from genome projects. • Computer-annotated supplement to SWISS-PROT. • Contains translations of all coding sequences in the EMBL Nucleotide Sequence Database which are not yet in SWISS-PROT. • MOUSE IN SWISS-PROT • The mouse has been selected as a model organism in • SWISS-PROT which means: • We aim to be as complete as possible. • We add new sequences and updates as quickly as possible while still providing a high level of annotation. • We provide cross-references to the Mouse Genome Database (MGD). • We maintain an index of MGD entries referenced in • SWISS-PROT: • http://www.expasy.ch/cgi-bin/lists?mgdtosp.txt CURRENT STATUS 3685 in TrEMBL  6992 mouse entries in total  3307 in SWISS-PROT DATA FLOW EMBL Manual annotation of TrEMBL entries by curator before addition to SWISS-PROT Translation Automatic annotation Literature  TrEMBL Sequence analysis tools External experts HOW TO CONTACT US WWW (EBI homepage): http://www.ebi.ac.uk E-mail (submissions): datasub@ebi.ac.uk E-mail: magrane@ebi.ac.uk FTP: ftp.ebi.ac.uk Telephone: + 44 (0)1223 464656 Fax: + 44 (0)1223 494468 Submissions  SWISS-PROT  Journal scan Example of SWISS-PROT mouse entry