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II. ESCRT-I, -II, -III cholesterol-enriched microdomain molecular coat tetraspannins. immature viral particle mature viral particle exosome. Gag Env viral genomic RNA. I. III. Cellular players. AP1, AP2, AP3 GGAs, Arf Cytoskeleton KIF4 Annexin-2 TIP-47 PI(4,5)P2 …. ?.
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II ESCRT-I, -II, -III cholesterol-enriched microdomain molecular coat tetraspannins immature viral particle mature viral particle exosome Gag Env viral genomic RNA I III Cellular players AP1, AP2, AP3 GGAs, Arf Cytoskeleton KIF4 Annexin-2 TIP-47 PI(4,5)P2 … ? microchannel Viral Assembly Compartments Pr55 Gag synthesis Tsg101 I II Alix Env transport Tsg101 III I II Alix III Sponge-like structure Golgi Lysosome