PET•CT cardiac perfusion and viability mismatch study

1. PET•CT cardiac perfusion and viability mismatch study Stress 13NH3 Perfusion 18FDG Viability Rest 13NH3 Perfusion 18FDG Viability • Perfusion-viability mismatch in 13N-NH3 PET perfusion and 18F-FDG PET viability study • Mismatch indicative of ischemic but viable myocardium - capable of return to normal contractility with revascularization • Patient identified as a candidate for revascularization. Source: Data Courtesy of University of Michigan

2. Cardiac PET Evaluation of Myocardial Perfusion and Metabolism Resting Perfusion Viability NH3 FDG Resting Perfusion Viability NH3 FDG Resting Perfusion Viability NH3 FDG Source: Data Courtesy of Cleveland Clinic Foundation, Cleveland OH, Dr. Neuman

3. 82Rb Cardiac PET/CT 16 Stress Rest Gated Stress Rest Gated Stress Rest Gated Stress Rest Gated 33 year old male, 79.5 kg (175 lbs.) Cardiac Stress, Rest and Gated PET slices. 16 Gate 82Rb Cardiac PET/CT Source: Data Courtesy of Medical Imaging Center, Grand Rapids, MI, USA, Dr. P. Shreve Data Courtesy of Cleveland Clinic Foundation, Cleveland, OH

4. Cardiac 82Rb PET Stress Rest Stress Rest Stress Rest Normal Myocardial Perfusion Static Stress and Rest Test Source: Data Courtesy of Cleveland Clinic Foundation, Cleveland OH, Dr. Neuman

5. Cardiac – Rule out Coronary Artery Disease • 47 year old patient with non-specific chest pain presented for evaluation to rule out coronary artery disease. • A PET•CT rest perfusion study was performed with Rb, along with a CT angiography of the coronary vessels. Source: Images courtesy of Emory Crawford Long Hospital, Atlanta, GA, Dr. Patterson