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Cancer testis - PowerPoint PPT Presentation

Tumor-specific chromosomal translocation

Yes. No. e.g. Osteosarcoma Chondrosarcoma Malignant fibrous histiocytome. Autologous tumor-CTL pair. cDNA library expression cloning. Novel tumor antigen. Search for HLA-anchor motif. Tumor-specific chromosomal translocation. e.g. Synovial sarcoma: SYT-SSX Ewing sarcoma: EWS-Fli1

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Cancer testis - PowerPoint PPT Presentation

Tumor-specific chromosomal translocation