'Histone deacetylases' presentation slideshows

Histone deacetylases - PowerPoint PPT Presentation

Ageing 2: Cancer

Ageing 2: Cancer

Ageing 2: Cancer. Review : The force of natural selection declines with ageing due to increase in extrinsic mortality (= weakening of natural selection) and reduction in reproduction with age (selection acts at reproduction). Review.

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701 views • 56 slides
Preparation of enzymatically active recombinant c lass III protein deacetylases

Preparation of enzymatically active recombinant c lass III protein deacetylases

Preparation of enzymatically active recombinant c lass III protein deacetylases. Brian J.North, Bjoern Schwer, Nidhi Ahuja, Brett Marshall, Eric Verdin By:. Importance of Review.

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383 views • 27 slides
Topic Next step: deciding which genes to clone Problem = correlating enzymes with genes

Topic Next step: deciding which genes to clone Problem = correlating enzymes with genes

Topic Next step: deciding which genes to clone Problem = correlating enzymes with genes Who matches the pH? Who localizes where? Which isoform if alternatively spliced? Clone several, using one known to work to find orthologs Use sequence to design primers to clone cDNA. Issues

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398 views • 24 slides
Transcriptional Signature of Histone Deacetylases in Breast cancer

Transcriptional Signature of Histone Deacetylases in Breast cancer

Transcriptional Signature of Histone Deacetylases in Breast cancer. Presented by: Dr Sahar A. El Shafei Professor and Head of Human Genetics Department Medical Research Institute Alexandria University. Breast cancer is the leading cancer in women worldwide.

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162 views • 15 slides
Progress of epigenetic therapy

Progress of epigenetic therapy

Progress of epigenetic therapy. Melissa Sylvester. intro. Moss and Wallrath demonstrated that in some cases reversal of cancer is possible, because of the connection between human disease and epigenetic silencing.

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105 views • 8 slides
Histone Deacetylase Pathway

Histone Deacetylase Pathway

The orderly regulation of gene transcription is a prerequisite for the maintenance of normal functions of the body's cells. If the transcriptional regulation of the gene is disordered, the cells may become cancerous. Recent studies have found that the occurrence of tumors is closely related to the imbalance between acetylation and deacetylation of core histones. In the organism, a pair of functionally antagonistic proteases is responsible for histone acetylation and deacetylation, namely histone acetyltransferase (HAT) and histone deacetylase (HDAC).

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24 views • 1 slides
Histone Deacetylase Pathway

Histone Deacetylase Pathway

The orderly regulation of gene transcription is a prerequisite for the maintenance of normal functions of the body's cells. If the transcriptional regulation of the gene is disordered, the cells may become cancerous. Recent studies have found that the occurrence of tumors is closely related to the imbalance between acetylation and deacetylation of core histones. In the organism, a pair of functionally antagonistic proteases is responsible for histone acetylation and deacetylation, namely histone acetyltransferase (HAT) and histone deacetylase (HDAC).

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29 views • 1 slides
Histone Deacetylase Pathway

Histone Deacetylase Pathway

The orderly regulation of gene transcription is a prerequisite for the maintenance of normal functions of the body's cells. If the transcriptional regulation of the gene is disordered, the cells may become cancerous. Recent studies have found that the occurrence of tumors is closely related to the imbalance between acetylation and deacetylation of core histones. In the organism, a pair of functionally antagonistic proteases is responsible for histone acetylation and deacetylation, namely histone acetyltransferase (HAT) and histone deacetylase (HDAC).

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28 views • 1 slides

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