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Engineering Antibodies (1) MSc Programme University of Nottingham 14 th February 2005

Engineering Antibodies (1) MSc Programme University of Nottingham 14 th February 2005

Engineering Antibodies (1) MSc Programme University of Nottingham 14 th February 2005. by Mike Clark, PhD Department of Pathology Division of Immunology Cambridge University UK www.path.cam.ac.uk/~mrc7/. Antibody based immunotherapeutics. IgG is the preferred class.

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688 views • 68 slides
Pharmacokinetic and Pharmacodynamic Considerations in the Development of Macromolecules

Pharmacokinetic and Pharmacodynamic Considerations in the Development of Macromolecules

Pharmacokinetic and Pharmacodynamic Considerations in the Development of Macromolecules. Pamela D. Garzone, Ph.D. OUTLINE OF LECTURE TOPICS. Macromolecules Interspecies Scaling Pharmacokinetic Characteristics Scientific Issues Pharmacodynamics Monoclonal Antibodies.

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954 views • 51 slides
A ligand binding enzyme linked immunosorbent assay (ELISA) experimental design usually

A ligand binding enzyme linked immunosorbent assay (ELISA) experimental design usually

Application of Design of Experiments using JMP to Develop a Universal Quantitative Method for Preclinical Pharmacokinetic Support Alok Rathi , Carina Carter, Qiang Qu, Jim McNally, Theresa Goletz. EMD Serono Research and Development Institute, Inc., Billerica, MA. Introduction.

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156 views • 8 slides
Suppl Figure 1

Suppl Figure 1

Suppl Figure 1. Growth characteristics of CHO-K1 wt and CKiD cells:

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184 views • 3 slides
-omab

-omab

Mouse spleen cells. Hybridoma. MOUSE. Ag Immunization. 1986. (Muromonab). Screening mouse Ig. Cell colture. -omab. Myeloma cells. hCH2. hCH1. hCL. mVL. hCH3. mVH. Mouse VH and VL. +. CHIMERIC. 1994. (Abiciximab). -ximab. Mouse mAb. Human CH and CL. 1994.

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228 views • 1 slides

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