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Complex Learning Disabilities. Comorbidity Subdiagnostic Impairments. LIFE BELOW THE DIAGNOSTIC HORIZON Domains of unappreciated impairment. Etiology. Often genes “+” disorder Males predominate. Genetic Factors. Familial Multigenerational. Environmental Factors. Tobacco Alcohol
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Complex Learning Disabilities Comorbidity Subdiagnostic Impairments
LIFE BELOW THEDIAGNOSTIC HORIZONDomains of unappreciated impairment
Etiology • Often genes “+” disorder • Males predominate
Genetic Factors • Familial • Multigenerational
Environmental Factors • Tobacco • Alcohol • Traumatic Brain Injury • Unilateral Hearing Loss
Genetics - Environment • Onset • Comorbidity • Course • Response to treatment • Outcome
Learning Disabilities are an expression of the underlying physiological adaption tothe causal pathology
Prevalence3-10%Diagnosis dependent rate 25% recognized Classroom – 301-3 affected
Five Topics • Genes, epigenetics and responses to demands to learn • Living below the diagnostic horizon • Reading • Math and OCD • Sleep and Learning
Epigenetics • Animal models • Famalial factors • Tics • Stereotypies • Handwriting • Responses
Environmental Exposure • Early difficulty • Poor response to high intensity effort • Impaired persistence
The Child’s Approach to Demands Genetics – exposure to stress Environment – poor stress reduction Epigenetics – poor stress tolerance
Attention Deficit Hyperactivity Disorder % 12 10 8 6 4 2 High Hyperactivity Attention Disability 12% per year Severity & Prevalence 12% per year Low Birth 2 4 6 8 10 12 14 16 18 20 17 5
Learning Disability % 8 6 4 2 High 5 – 8% per year 15 – 20% per year Severity & Prevalence Low Birth 4 9-10 13 18
Distribution of Learning Disability by Age of Onset %
Distribution of ADHD by Learning Disability and Age of Onset %
Distribution of Learning Disability by Age Diagnosed %
Distribution of ADHD by Learning Disability and Age Diagnosed %
Assessment • Etiology • Course • Familial Course
Phonologic Errors Phonetic Spelling errors
Many of the slides in this presentation are from the work of Pelli et al Nature (423) 752-756; 2003 or Wilson et al Nature (423) 696-697; 2003.
Efficiency Level in Reading 1 n = number of letters in word
1,000 Human 100 Energy (relative to noise) Ideal 10 1 10 Word Length (letters)
0.1 Efficiency 0.01 1 10 Word Length (letters)
5 most common 3 letter words: • The • And • Was • For • His
Least frequent word “his” is encountered: • 100 times per hour • 400,000 times per decade if reading 1 hour a day
Letter Recognition • All or not very well phonemena
Word Effect Coin C Join J
Comprehension • Decoding impairs comprehension • Comprehension improves decoding
Rset Pclae Rghit Ltteer Lsat Tihng Iprmoetnt Bcuseae porbelm Raed Rscheearch Elingsh Mese Still Lteter Ervey Word wlohe
Comprehension Improves Decoding Skills Aoccdrnig to rscheearch at an Elingsh uinervtisy, it deosn’t mttaer in what oredr the ltteers in a word are, the olny iprometnt tihng is that frist and lsat ltteer is at the rghit pclae. The rset can be a toatl mses and you can still raed it wouthit porbelm. This is bcuseae we do not raed ervey lteter by istlef but the word as a wlohe.
Reversals are Frequent b/d p/d p/b m/w was/saw on/no
Rarely 6/9 2/6 3/8
Assessment • IQ • Reading rate • Standard scores • Comprehension
Signs Alphabet Letter Sounds Phonics Words Careful Reading Comprehension Rapid Reading Skipping Context Context and Skipping Reading Skills Progression
Successful Intervention • Early recognition • Intensive services • Skill building • Success • Avoid teasing
Order of Improvement • Phonology • Phonetics • Reading speed • Spelling (last and least)
Math • Cardinality • Numerosity • Ordinality
Math • Reading is very difficult ( + x ) • Multiple steps • Poor tool use • Self confidence • Anxiety • Written • Oral • Can’t do “seems about right” check
Common Error Patterns 4 5 8 3 + 2 + 6 - 3 - 5 6 11 11 8
Math - OCD Developmental acquisition of: • Ordinality • Cardinality • Number object correspondence • 0-5 • Likelihood • Risks • Risk Perception
OCD • Alterations • Intact math-skill • Deficit of inferential thinking • Application of knowledge
OCD – Memory Deficits OCD can be quite complex in people with memory deficits