Pilot proposal submitted to Ministry of Human Resource Development Under the Scheme on

1. Development of VIRTUAL LAB solutions through ICT on Microwave Biosensors Applications towards Early & Efficient Diagnosis of Health Risks in Rural Zones of India. • Pilot proposal submitted to • Ministry of Human Resource Development • Under the Scheme on • “National Mission on Education through Information and Technology” Dr. K. S. Daya Microwave Physics Laboratory Department of physics & Computer Science Dayalbagh Educational Institute Dayalbagh, Agra –282 110

2. Virtual Lab realisation on NON-INVASIVE PLANAR MICROWAVE SENSOR for BLOOD GLUCOSE DETECTION RAPID DETECTION MICROWAVE SENSOR FOR THE PRESENCE OF PATHOGENIC BACTERIA IN DRINKING WATER

3. Design objective Present proposal aims to develop Virtual Lab solutions using devices based on simple microwave structures for effectiveearly diagnosis of health risks. - Design & development of biosensors. • Developing a device by integrating the developed sensor, data analyser & the data converter. • Fusing the developed device to a communication gadget.

4. Motivation Technology advancements in the field of healthcare and biological sciences has overwhelmingly influenced our lifestyle and lifespan. However, advanced technologies today seem incomplete • due to the complexity of the biological systems • for its drawbacks in providing easy and fast information as it requires # highly priced consumables, # considerable time # skilled manpower, none of which are easily available.

5. Motivation- Cont… Hence… understanding the health risks and the health status of individuals in the rural India has not been viable till date. Over half the population of India are inhabited in rural or geographically challenging locations, thus any statistics available on the health is incomplete.

6. Working Principle • Interaction between microwaves and matter • the electric field passes through the dielectric medium, • electric field affects medium parameter called permittivity (dielectric constant) • Measuring the dielectric properties of a material can indirectly measure other properties that have a correlation to the material For Eg:- Dielectric constant of blood increases with increase in glucose level in blood

7. Advantages • Microwave sensors are very sensitive to change in dielectric constant and most of biological substances either have high dielectric proteins or are dielectric proteins themselves. • Microwave sensor does not require any reagents or chemical, thus an indigenous solution without interdependencies • Unlike biological methods, results are immediate.

8. Other Benefits • Easy to use • No technical expertise required • Can be a completely portable systems • No reagents or chemical required, thus eliminating the need of supply chain for transporting chemicals to remote locations • Gives autonomy to the user resulting in better health safety concern

9. Sensor Design & Development Non Invasive Blood Glucometer Low cost, NO-PRICK and easy to use solution for continuous self monitoring of blood glucose .

10. Thus there is an immediate need for a easy and safe solution which will overcome:- • The psychological hassle to a prick. • Blood related safety concerns (infections) • Requirement of skilled manpower. • Requirements of consumables of conventional ready to use • invasive gluco-meters. • And … • Provides with an indigenous and user friendly self monitoring systems to the under privileged and elderly

11. Sensor Design & Development Rapid Pathogen Sensor Low cost, user friendly and easy to use solution for consistent monitoring of bacterial pathogens in water.

12. There is an immediate need for a easy and rapid solution which will overcome:- • Cost • Prolonged TAT • Result related problems on consistency / repeatability & reproducibility • Requirement of skilled manpower. • Requirement for instruments. • Requirements of consumables for conventional and test kits.

13. Proof of Principle Microstrip line type sensor Sensitivity : 8.71 mg/dl per MHz % Error : 15%

14. Frequency shift and Glucose level in blood

15. Sample - Simulation Results

16. Realising the VIRTUAL LAB Solution Base Architecture • Hand held device (Mobile phone) used by a patient. • Conversion of microwave data • Test Value displayed. • Data Interpretation and advice on future course of action. (through voice, preferably in local language) • Simultaneously transmits the information to a Physician / Hospital / Repository

17. Architecture for realising Virtual Lab Non-Invasive Glucometer (SMS) (VOICE)

18. Architecture for realising Virtual Lab Rapid Bacterial Sensing

19. Information to a Database Communication (SMS) to Health care personnel

20. Alike models • DIAdvisor – Ongoing project titled the PERSONAL HEALTH SYSTEMS through ICT under the Seventh Framework Programme (FP7) of the European Union (EU). • Project duration – 2008 to 2012 • Project cost - €9,300,000

21. Timeline & Deliverables for thePILOT PHASE

22. ProposedBudget for PILOT PHASE

24. Details of Recurring Budget

25. Thank You