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IDF EUROPE GA MEETING MUNICH,2005. SURVEY ON DIABETES CARE IN EIGHT CENTRAL EASTERN EUROPEAN COUNTRIES (THE DEPAC STUDY). Survey of diabetes care in eight new EU accessing countries.
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IDF EUROPE GA MEETINGMUNICH,2005 SURVEY ON DIABETES CARE IN EIGHT CENTRAL EASTERN EUROPEAN COUNTRIES (THE DEPAC STUDY)
Survey of diabetes care in eight new EU accessing countries • Planned and organized by the Diabetes Experts’ Panel from Accessing Countries (DEPAC) established in May 2004 • PROTOCOL A multi-centre, randomised, non-interventional survey assessing metabolic control, short- and long term complications, and diabetes care of patients in 8 EU accessing countries
Timelines of the survey(Critical milestones) • Preparations phase • Final protocol approved 22 Oct 2004 • Translation of protocol into local languages 5 Nov • Investigators’ meetings in countries 19 Nov–17 Dec • Operations phase • Collection of data started 03 Jan 2005 • Collection of data completed 28 Feb • Analysis phase • Statistical analysis complete 20 March • Integrated survey report complete (abstract to EASD) 28 March
Number of patients (planned:10 000; collected:11 085) EST 200 HU 1800 LAT 300 CZ 2000 LIT 300 SLO300 SK 1100PL 4000
CLASSIFICATION • Type 1 DM: 2497 22.85% • Type 2 DM: 8231 75.31% • Other Types of DM: 202 1.84%
AGE AND DIABETES DURATION • Mean age (years): Type 1 men:37,07 Type 2:61,08 women: 36,7063,17 • Diabetes duration (years): Type 1 men: 13,21 Type 2 :9,61 women: 14,3710,68
INSULIN TREATMENT • Human insulins: Type 1 DM: 70.10% Type 2 DM: 40.50% • Analog insulins: Type 1 : 49.03% Type 2 : 10.82%
ORAL TREATMENT • Metformin Sulphonyloureas Type 2 DM: 50.70%39.0% • AcarboseOral + Insulin Type 2 : 10.0%14.20%
Results: metabolic control and lipids • Poor metabolic control (HbA1c > 8%) Type 1 DM: 49.10% Type 2 DM: 36.77% • Dyslipidemia (high serum lipids) Type 1 : 29.03% Type 2 : 66.82%
Results: microvascular complications • Retinopathy Type 1 : 41.30% Type 2 : 32.34% • Nephropathy Type 1 : 28.46% Type 2 : 25.02% • Neuropathy Type 1 : 31.79% Type 2 : 30.22%
Results: cardiovascular complications • Hypertension Type 1 : 30.52% Type 2 : 79.49% • Cardiovascular disease Type 1 : 8.58% Type 2 : 43.34%
SURVEY ANALYSIS The only differences in diabetic complications between men and women which reached statistically significant levels were: • hypertension (P<0.01), • myocardial infarction (P<0.001), • peripheral arterial disease (P<0.001) • and diabetic foot ulcer (P<0.001)
CONCLUSIONS The results should be a platform for further goals on country and EU levels: • highlighting the costs and benefits from diabetes treatment, • creating ways of health promotion and health monitoring, • increasing patient empowerment through education , - discussion about the status of National Diabetes Programmes in each countries.