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Epidemiology What is a communicable disease portal of exit (through which infectious agent leaves host) portal of entry spread by direct contact or through contami- nation. Non-communicable disease individual’s normal flora environmental reservoir What is a reservoir?
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Epidemiology What is a communicable disease portal of exit (through which infectious agent leaves host) portal of entry spread by direct contact or through contami- nation
Non-communicable disease individual’s normal flora environmental reservoir What is a reservoir? often infected people carriers are asymptomatic zoonoses- animal diseases can be transmitted to humans Smallpox was eradicated; rabies cannot be
How are diseases characterized? Rate of spread of disease morbidity rate- high if disease spreads rapidly mortality rate- death rate endemic diseases are always present epidemics
How is disease transmitted? Horizontal or vertical Direct contact Fomites (indirect) Droplets Food/water Air Vectors Who is susceptible? natural immunity; general health; age; gender, etc.
Methods for studying epidemiology Descriptive- who, what, when, where Analytical- risk factors Experimental- how to control disease Several agencies exist to monitor disease (CDC, public health department, WHO)
How can diseases be eradicated? vaccination; sanitation, etc. Emerging diseases- why does that happen? new versions of microbes breakdown of public health structure changes in human behavior/activity travel commerce technology etc.
What are the reservoirs? Other patients Health care workers The hospital environment Patient’s own normal flora invasive procedures immune compromise
How are they spread? How can they be prevented? Universal precautions Standard precautions (p. 502) handwashing gloves personal protection (masks, etc.) environmental control sharps patient placement
Summary • How disease spreads- mechanism and rate • Where do infectious agents come from? • How are they transmitted? • Who is susceptible? • How can it be controlled?