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ABIRAPRO 250mg Tablet (Abiraterone acetate)

ABIRAPRO 250mg Tablet (Abiraterone acetate) is an anticancer drug used in men along with another drug called prednisone for the treatment of prostate cancer that has spread to other parts of the body@myapplepharma

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ABIRAPRO 250mg Tablet (Abiraterone acetate)

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  1. Abirapro 250mg Abirapro is belongs to type of anti-cancer medication that will act by decline the androgen production in the body. Androgen is a male hormone that canmaintance the tumor cell in prostate glands, the main ingredient which is used as abiraterone . Actually thisdrug is given by co administration with prednisolone, a steroid which reduce the liability of side effects produced by Abiraterone. MECHANISM OF ACTION Androgens are balance the production of malignant in prostate. Abiraprois belongs to anti androgen drugs, thatcauses to suppress the enzyme 17α-hydroxylase C 17, 20-lyase (CYP17), it is involves in androgen conglomerate. Reduce the serum testosterone level. Declined the tumor cell occurred. SAFETY AND WARNING OF ABIRAPRO Anyallergy, serious liver problem or pregnant in patient, Abiraprotherapy should be stopped Avoid taking of other medications, i.e prescription, over-the-counter, vitamins, herbal remedies, etc be sure to inform the doctors before the

  2. treatment. Do not take Aspirin administrated and products containing aspirin till doctor particularly allow the drug. PHARMACOKINETICS Absorption: Time to maximum plasma concentration of Abiraprotablet takes 12 hours. Distribution: Maximum bound to the human plasma protein like albumin and alpha-1 acid glycoprotein. Metabolism: Themain two metabolites of Abiraterone in human plasma are Abiraterone sulphate and N-oxide Abiraterone sulphate. Excretion: The drug mainly excreted in 88% feces and 5% in urine Half-life of tablet Abirapro is 12 ± 5 hours. DRUG INTERACTION Interaction of Abirapro with dextromethorphan will raises the Cmax and AUC of dextromethorphan Interaction Abirapro with strong CYP3A inhibitors or inducers , concomitant use with caution because pharmacokinetics is not evaluated.

  3. PREGNANCY Pregnancy category X: while ontherapy with Abirapro tablet if women become pregnant, immediately stop the drug and give counseling to the women. Abirapro tablet is not recommended for women. STORAGE The drug stored at 15℃ - 30℃. Keep the drug in dry place. MISSED DOSE If patient missed the dose ofAbirapro, that missed dose will be skipped and follow the regular dosing schedule. SIDE EFFECTS Common effects Fatigue, Arthralgia, Hypertension, Nausea, edema, Hypokalemia, Diarrhea, vomiting, Cough, headache, Glucocorticoid deficiency,Mineral corticoid deficiency, Hepatotoxicity, Hypertension, Decrease in ka leve CONTACT US : Email Id : info@myapplepharma.com Phone No : 91-9987711567 Website :https://myapplepharma.com/abirapro-250mg.php

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