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Stent Redesign . Whit Miller BME Senior Design Spring 2001. In 1999, US Physicians performed over 500,000 PCTA procedures involving a stent placement. Within one year of de- ployment, 50% of stents illicit a restenosis. Market Analysis. Making a Better Mousetrap.
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Stent Redesign Whit Miller BME Senior Design Spring 2001
In 1999, US Physicians performed over 500,000 PCTA procedures involving a stent placement Within one year of de- ployment, 50% of stents illicit a restenosis. Market Analysis
Making a Better Mousetrap • Current stents are bare metal • A covered stent would have at least two advantages • Limit SMC proliferation at the deployment site • Expedite endothelialization
SES Vs Balloon-Deployed • Self-Expanding Stents are considered superior for two reasons • Maximize deployment precision • Minimize catheterization time
Current Technology • Best of the Current Covered SESs • The Wallgraft and Corvita
The need for improvement • Current covered SES have limited proven ability to prevent restenosis • Neurovascular interventionalists have limited options for cerebral stenting
Project Goals • Select a stent covering • Covering will be mated with superior stent design • Investigate commercial polymers and cadaveric decellularlized material • Subject covering to filtration, deployment constraints