1 / 9

Report from the Biostatistics and Data Management Center

Report from the Biostatistics and Data Management Center. Constantine Gatsonis, PhD ACRIN Biostatistics and Data Management Center Brown University Providence, RI. BDMC 2008-2009: Highlights. Major emphasis on developing and launching new studies:

shina
Download Presentation

Report from the Biostatistics and Data Management Center

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Report from the Biostatistics andData Management Center Constantine Gatsonis, PhD ACRIN Biostatistics and Data Management Center Brown University Providence, RI

  2. BDMC 2008-2009: Highlights • Major emphasis on developing and launching new studies: • Cancer: 6681, 6682, 6683, 6684, 6685, 6686, 6687, 6688, 6689, 6690, 6691 • Cardiovascular: 4005 • Analysis for primary and secondary papers and abstracts in several protocols: • 6652, 6654, 6657, 6660, 6661, 6664, 6665, 6666, 6667, 6668, 6673, 6677, 6683

  3. Themes of new studies • Imaging-based biomarkers for predicting response to therapy and long term outcomes. • Majority of new studies • CAD evaluation. • Accuracy in diagnosis and staging. • Diagnostic test impact on outcomes. • Significant methodologic and practical challenges

  4. Predicting response • Cu64-ATSM PET for cervical cancer (6682) • FMISO in glioblastoma (6684) • DCE-MRI, DSC-MRI in glioblastoma(6686) • F-Fluoride PET in prostate cancer (6687) • FLT PET in breast cancer (6688) • FLT PET and DCE-MRI in glioblastoma (6689) • Optimal imaging in breast cancer (6691)

  5. Accuracy: diagnosis and staging • CAD for CT Colonography (6681) • CAD for mammography (6683) • PET/CT for head and neck cancer (6685) • CDE-MRI and DCE-CT for HCC in liver transplant candidates (6690)

  6. Impact on outcomes • CT angiography in the emergency room: Randomized comparison to usual care (4005). • Preoperative MRI for women with breast cancer: Randomized study of impact on surgical outcomes, recurrence, quality of life and cost. (in development)

  7. Analysis and publications • Analysis for primary and secondary papers and abstracts in several protocols: • 6652, 6654, 6657, 6660, 6661, 6664, 6665, 6666, 6667, 6668, 6673, 6677, 6683 • Solid presence at RSNA. • Abstracts at ASCO and other conferences. • Publications volume needs to increase. • Paper writing needs more attention and energy.

  8. Informatics and Data Management • Needs identified (from last year’s presentation): • Fully electronic data management • Improved data entry capabilities • Automated system for tracking data queries. • Progress update: • Finally close to making decisions on choice of new system. • Transition will be a significant undertaking.

  9. It has been quite a ride!

More Related