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MCU overexpression increases mitochondrial Ca 2 accumulation in intact and permeabilized cells, buffers cytosolic [Ca 2 ] rises, and sensitizes to apoptotic stimuli; GFP-tagged MCU demonstrates mitochondrial localization and indicates a putative membrane topology.
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MCU overexpression increases mitochondrial Ca2 accumulation in intact and permeabilized cells, buffers cytosolic [Ca2] rises, and sensitizes to apoptotic stimuli; GFP-tagged MCU demonstrates mitochondrial localization and indicates a putative membrane topology. D De Stefani et al. Nature000, 1-5 (2011) doi:10.1038/nature10230