BMS208 Human Nutrition

1. BMS208 Human Nutrition Topic 4: The Carbohydrates: Sugars, Starches, and Fibers Chris Blanchard

2. Learning objectives • Classify carbohydrates as mono-, di- or polysaccharides. • Explain the two major types of dietary fibers and their uses in the body. • Trace the digestion and absorption of carbohydrates. • List the enzymes used in the digestion of carbohydrates. • Describe lactose intolerance symptoms, prevalence and treatment. • List the major uses of glucose in the body. • Discuss the hormones used by the body to maintain normal blood glucose concentration.

3. Learning objectives (cont’) • List the major types of diabetes. • Explain glycemic load and the pros and cons of its use in meal planning. • Identify the major sources of added sugars in the diet. • Describe the effect of added sugars on dental health. • Identify the health benefits of a diet rich in starch and fiber. • Identify the Daily Value and DRI for fiber and methods to increase fiber in the diet. • List the common alternatives to sugar in the diet.

4. The Chemist’s View of Carbohydrates • Carbohydrates are made of carbon, hydrogen and oxygen atoms. • These atoms form chemical bonds that follow the laws of nature.

5. The Simple Carbohydrates • Monosaccharrides are single sugars (most are hexoses). • Glucose serves as the essential energy source, and is commonly known as blood sugar or dextrose. • Fructose is the sweetest, occurs naturally in honey and fruits, and is added to many foods in the form of high-fructose corn syrup. • Galactoserarely occurs naturally as a single sugar.

6. Nomenclature

7. Monsaccharides

8. Disaccharides • Pairs of monosaccharides, one of which is always glucose • Condensation reactions link monosaccharides together. • Hydrolysis reactions split molecules and commonly occur during digestion. • Maltose consists of two glucose units. It is produced during the germination of seeds and fermentation. • Sucrose is fructose and glucose combined. It is refined from sugarcane and sugar beets, tastes sweet, and is readily available. • Lactose is galactose and glucose combined. It is found in milk and milk products.

9. Condensation and Hydrolysis

10. The Complex Carbohydrates • Few (oligosaccharides) or many (polysaccharides) glucose units bound/linked together in • May be straight or branched chains. • Examples: Glycogen, Starch, Dietary Fibre

11. Glycogen Glycogen • Storage form of glucose in the body • Provides a rapid release of energy when needed

12. Starch (amylopectin) Starch (amylose) Starch • Storage form of glucose in plants • Found in grains, tubers, and legumes

13. Dietary fiber • Provide structure in plants • Very diverse • Cannot be broken down by human enzymes. • Soluble fibers • Viscous and can be digested by intestinal bacteria Found in fruits and vegetables. • Insoluble fibers • Non-viscous and are not digested by intestinal bacteria. • Found in grains and vegetables.

14. Starch vs Cellulose

15. Fiber Sources • Dietary fibers are found in plant foods. • Functional fibers are health-benefiting fibers that are added to foods or supplements. • Total fiber considers both dietary and functional fibers.

16. Resistant starches • Escape digestion • Found in legumes, raw potatoes and unripe bananas.

17. Phytic acid • Also known as phytate • Has a close association with fiber • Binds some minerals.

18. Carbohydrate Digestion • In the mouth, • Salivary enzyme amylase begins to hydrolyze starch into short polysaccharides and maltose. • In the stomach, • Acid continues to hydrolyze starch • Fiberdelays gastric emptying and provides a feeling of fullness (satiety).

19. Carbohydrate Digestion • In the small intestine, • Pancreatic amylase among other enzymes (maltase, sucrase, and lactase) hydrolyzes starches to disaccharides and monosaccharides. • In the large intestine, • Fibers remain and attract water, • Soften stools and ferment.

21. Carbohydrate Absorption • Primarily takes place in the small intestine • Glucose and galactose are absorbed by active transport. • Fructose is absorbed by facilitated diffusion.

22. Small intestine Carbohydrate Absorption Monosaccharides, the end products of carbohydrate digestion, enter the capillaries of the intestinal villi. In the liver, galactose and fructose are converted to glucose. Monosaccharides travel to the liver via the portal vein.

23. Lactose Intolerance • Symptoms include bloating, abdominal discomfort, and diarrhea. • Causes include lactase deficiency due to a natural decrease that occurs with aging or damaged intestinal villi. • Prevalence • Lowest in Scandinavians and northern Europeans • Highest in Southeast Asians and native North Americans

24. Lactose Intolerance - Dietary Changes • Increase consumption of milk products gradually. • Mix dairy with other foods. • Spread dairy intake throughout the day. • Use of acidophilus milk, yogurt, and kefir (fermented products) • Use of enzymes • Individualization of diets • Must be careful that vitamin and mineraldeficiencies do not develop

25. Carbohydrate Metabolism • The body stores glucose as glycogen in liver and muscle cells. • The body uses glucose for energy if glycogen stores are available. • If glycogen stores are depleted, the body makes glucose from protein. • Gluconeogenesis is the conversion of protein to glucose. • Protein-sparing action is having adequate carbohydrate in the diet to prevent the breakdown of protein for energy.

26. Carbohydrate Metabolism • Making ketone bodies from fat fragments • The accumulation of ketone bodies in the blood is called ketosis. • Ketosis upsets the acid-base balance in the body. • The body can use glucose to make body fat when carbohydrates are consumed excessively.

27. Constancy of Blood Glucose • Need to maintain glucose homeostasis • Low blood glucose may cause dizziness and weakness. • High blood glucose may cause fatigue. • Extreme fluctuations can be fatal.

28. Constancy of Blood Glucose • The Regulating Hormones • Insulin moves glucose into the cells and helps to lower blood sugar levels. • Glucagon brings glucose out of storage and raises blood sugar levels. • Epinephrine acts quickly to bring glucose out of storage during times of stress.

29. Constancy of Blood Glucose • Glucose can be maintained within the normal range by eating balanced meals regularly with adequate complex carbohydrates. • Blood glucose can fall outside the normal range with hypoglycemia or diabetes.

30. Diabetes and Hypoglycemia • Diabetes • Type 1 diabetes is the less common type with no insulin produced by the body. • Type 2 diabetes is the more common type where fat cells resist insulin. • Prediabetes is blood glucose that is higher than normal but below the diagnosis of diabetes. • Hypoglycemia is low blood glucose and can often be controlled by dietary changes.

31. Glycemic response • Glycemic response: how quickly the blood glucose rises and elicits an insulin response. • Glycemic index: classifies foods according to their potential for raising blood glucose. • Glycemic load: refers to a food’s glycemic index and the amount of carbohydrate the food contains. • The benefit of the glycemic index is controversial.

32. Glycemic Index

33. Health Effects of Sugars • Sugar poses no major health problem except dental caries. • Excessive intakes may displace nutrients and contribute to obesity. • Consuming foods with added sugars should be limited. • Naturally occurring sugars from fruits, vegetables and milk are acceptable sources.

34. Health Effects of Sugars • Foods with added sugars have sugars listed as a first ingredient. • Nutrient deficiencies may develop from the intake of empty kcalories. • Just because a substance is natural does not mean it is nutritious. (Example: honey)

35. Dental caries • May be caused by bacteria residing in dental plaque fermenting sugars from our diet

36. Controversies Surrounding Sugars • Excessive sugar intake can contribute to the development of body fat. • Sugar may be able to alter blood lipid levels and contribute to heart disease in some. • There is no scientific evidence that sugar causes misbehavior in children and criminal behavior in adults. • There is a theory that sugar increases serotonin levels, which can lead to cravings and addictions. This seems unlikely.

37. Recommended Intakes of Sugars • Added sugars can be included in the diet as part of discretionary kCalories. • Dietary Guidelines recommend limited intake of foods and beverages that are high in added sugars. • DRI suggest added sugars should contribute no more than 25% of a day’s total energy intake.

38. Health Effects of Starch and Fibers • Fiber may provide some protection from heart disease and stroke • Soluble fibersbind with bile and thereby lower blood cholesterol levels. • Fiber may also displace fat in the diet. • Reduce the risk of type 2 diabetes by decreasing glucose absorption • Enhance the health of the GI tract which can then block the absorption of unwanted particles • May protect against colon cancer by removing potential cancer-causing agents from the body

39. Health Effects of Starch and Fibers • Promote weight control because complex carbohydrates provide less fat and added sugar. • Harmful effects of excessive fiber intake • Displacesenergy and nutrient-dense foods • Abdominal discomfort and distention • May interfere with nutrient absorption

40. Recommended Intakes of Carbohydrates • RDA for carbohydrate is 130 g per day, or 45-65% of energy intake. • Daily Value is 300 grams per day. • Dietary Guidelines encourage a variety of whole grains, vegetables, fruits and legumes daily. • Healthy People 2010 recommends six servings of grains and five servings of fruits and vegetables.

41. Recommended Intakes of Fiber • FDA recommends 25 grams for a 2,000-kcalorie diet. • DRI at 14 g per 1000 kcalorie intake (28 g for a 2,000 kcalorie diet) • American Dietetic Association recommends 20-35 g per day. • World Health Organization suggests no more than 40 g per day.

42. From Guidelines to Groceries • Grains – encourage whole grains • Vegetables – starchy and nonstarchy vegetables differ in carbohydrate content • Fruits – vary in water, fiber and sugar content • Milks and Milk Products – contain carbohydrate; cheese is low • Meat and Meat Alternates – meats are low but nuts and legumes have some carbohydrate • Food labels list grams of carbohydrate, fiber and sugar; starch grams can be calculated.

45. Alternatives to Sugar • Artificial sweeteners (nonnutritive sweeteners) • Sugar replacers

46. Artificial Sweeteners • Saccharin • Aspartame • Acesulfame-K (acesulfame potassium) • Sucralose • Neotame • Tagatose • Alitame • Cyclamate

47. Saccharin • Trade names: Sweet ‘n Low • Relative sweetness: 450X • Used primarily in soft drinks and as a tabletop sweetener • Rapidly excreted in the urine • Does not accumulate in the body • Initial fears that excessive amounts may be linked to cancer appear to be unfounded.

48. Aspartame • Trade name: Nutrasweet, Equal, NutraTaste • Relative sweetness: 200X • General purpose sweetener • Not suitable for for those with phenylketonuria • Excessive intake should be avoided by those with epilepsy

49. Acesulfame potassium • Trade name: Sunette, Sweet One, Sweet ‘n Safe • Relative sweetness: 200X • Organic salt • Passes through the body unchanged

50. Sucralose • Trade name: Splenda • Relative sweetness: 600X • Made from sugar: • 3 OH groups replaced by Cl • Passes through GI undigested and unabsorbed