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Aim : How does protein synthesis occur in the cytoplasm?. Do Now : Transcription and Translation Questions. HW : Castle Learning – Complete any Incomplete Assignments. Protein Synthesis Bingo. DNA mRNA Amino Acid. TAC CCA TTA AAC CTT TTT GCA AGC TAG CAT AAA AGA
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Aim: How does protein synthesis occur in the cytoplasm? Do Now: Transcription and Translation Questions HW: Castle Learning – Complete any Incomplete Assignments
Protein Synthesis Bingo DNA mRNA Amino Acid TAC CCA TTA AAC CTT TTT GCA AGC TAG CAT AAA AGA ACT AUG Methionine • Why is it difficult to play Protein Synthesis Bingo? • What additional information is required to play? Why?
DNA mRNA mRNA Protein Review: Steps for Making A Protein • Transcription: • Translation:
Codon Amino Acid Why does the mRNA leave the nucleus? • mRNA now in the cytoplasm will move to a ribosome where proteins are made. • How many mRNA bases = 1 amino acid? • Codon (3 mRNA bases) = 1 amino acid.
Another special type of RNA, called tRNA, transports the amino acids in the cytoplasm to the ribosomes to form proteins. How do you think the amino acids, which are free floating in the cytoplasm, get to the ribosome?
mRNA vs. tRNA Messenger RNA Transfer RNA • Single Helix Structure • Carries copy of instructions from nucleus to ribosome • Loop (clover leaf) Structure • Carries amino acids to the ribosome
Transcription – Translation Practice DNA RNA Protein A T C G C T U A Tyrosine G C Arginine G A
DNA RNA Protein Let’s try This One Together G C C A A T A G C C G Arginine G U Leucine U A U Serine C G
Transcription - Translation DNA Segment #1 DNA Segment #2 CCGTATATG AAGGCAGCC
DNA Bingo = DINGO DNA / mRNA / Amino Acid TAC CCA TTA AAC CTT TTT GCA AGC TAG CAT AAA AGA ACT • AUG -MET (START) • GGU – GLY • AAU – ASP • UUG – LEU • GAA – GLU • AAA – LYS • CGU - ARG • UCG – CYS • AUC – ISO • GUA - VAL • UUU – PHE • UCU – SER • UGA – STOP