1 / 1

Rhodium(I)-Catalyzed Hydroacylation Promoted by Chelating Amines

Rhodium(I)-Catalyzed Hydroacylation Promoted by Chelating Amines Holly D. Bendorf , Lycoming College, Williamsport, PA 17701.

skyla
Download Presentation

Rhodium(I)-Catalyzed Hydroacylation Promoted by Chelating Amines

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Rhodium(I)-Catalyzed Hydroacylation Promoted by Chelating Amines Holly D. Bendorf, Lycoming College, Williamsport, PA 17701 Benzazepines (n = 1) and benzazocines (n = 2) exhibit a broad range of biological activity. Our goal is to develop syntheses of these compounds that emphasize the efficient use of chemical resources, much of which are derived from petroleum. To this end, rhodium-catalyzed hydroacylation is an attractive strategy due to its inherent atom economy and mild reaction conditions. The chemistry developed in our laboratory exploits chelating allyl amines, which readily undergo hydroacylation and produce the desired compounds in moderate to high yields.

More Related