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ELECTRONIC TONGUE

ELECTRONIC TONGUE. BY R.PAVAN KUMAR, RIPER-ANANTAPUR. WHAT IS ELECTRONIC TONGUE ?. The electronic tongue is an instrument that measures and compares tastes.

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ELECTRONIC TONGUE

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  1. ELECTRONIC TONGUE BY R.PAVAN KUMAR, RIPER-ANANTAPUR.

  2. WHAT IS ELECTRONIC TONGUE? • The electronic tongue is an instrument that measures and compares tastes. • It is an analytical instrument comprising an array of non-specific, low selective chemical sensors with cross-sensitivity to different components in solution, and an appropriate method of pattern recognition and/or multivariate calibration for the data processing.

  3. MAIN NEED IN PHARMACY FIELD • Assessment of the taste of oral drug the preparation-Major interest • To date, only method employed for determination of taste intensity was human sensory test. • To facilitate the work and address the difficulties associated with human panel test, a safe,reliable, fast analyzing objective instrument was developed called “Electronic Tongue” .

  4. PRINCIPLE Utilization of non-specific or low-selective potentiometric chemical sensors with enhanced cross-sensitivity to as many different components in solution as possible.

  5. CORRELATION WITH HUMAN TONGUE • Mechanism involved for taste recognition shows the same three levels in both.

  6. INSTRUMENTATION • Liquid Autosampler • ChemicalSensoror Sensor array • Acquisition System • Data Processing System

  7. CHEMICAL SENSOR ???? Chemical sensors are small devices that perform transformation of chemical or biochemical information of a qualitative or quantitative type into an analytical useful signal by the process of chemical interaction between sample and sensors. • Currently these technologies are based on electrochemical sensors(POTENTIOMETRIC). • Other sensing methods applied is voltammeter.

  8. The detecting sensor part consist of lipid/polymer membranes and act as the working electrodes. • The reference electrodes -Ag/AgCl. • Electrode charge density of the lipid/polymer membrane surface and ion distribution near the surface of the membrane is changed due to sample. • Therefore the total electrical charge on the lipid membrane gives the response membrane electric potential for the substances.

  9. ACQUISITION SYTEM • The acquisition system establishes the communication between the sensor array and data processing system. • Converts the electrical signals from sensor array to digital signals with less distortion. • Amplifier must be present as the electrical signals from the sensors are always small.

  10. DATA PROCESSING SYSTEMS • Chemometric techniques a type of multivariate statistic used in the analytical field provide data processing, which consist of recognition, classification and identification and multivariate calibration.

  11. APPLICATIONS • Quantify taste masking efficiency of formulations. • Analyze medicines stability in terms of taste. • Benchmark target products. • Analyze flavor ageing in beverages. • Quantify bitterness or “spicy level” of drinks or dissolved compounds.

  12. CONCLUSION Electronic tongues are emerging, promising and proved to be a valuable tool for assessment and prediction of the taste of pharmaceuticals and related products.

  13. THANK YOU

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