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Explore the statistics and geometry of cortical connections, including long-range axonal connections, micro-circuits, and the mini-architecture of the cerebral cortex. Topics include functional and anatomical connectivity, species comparison, spatial levels of connectivity, and neural plasticity.
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18th May, Morning Session IStatistics and geometry of neuronal connections Chair: Noritaka Ichinohe Lab for Cortical Organization and Systematics Brain Science Institute, RIKEN Questions The statistics of the cortical connections: long-range axonal connections and micro-circuits The mini-architecture of the cerebral cortex. The on-board micro-circuitry, dendritic growth, trees bifurcations (development of connectivity) and plasticity
Topics • 1. Bringing together functional and anatomical connectivity • 2. Species comparison and bridging (human, monkey, rodent) 1. McIntosh 2. Van Essen
3. Exploring different spatial levels of connectivity (area to area, microcircuitry etc.) and structures (area, column, layer etc.) 1. McIntosh 2. Van Essen (macroscopic area to area connectivity) 3. Rockland (long-range+local circuit) 4. Silberberg (local circuit) Spatial and temporal resolution of the methods (Cognitive Neuroscience, eds. Gazzaniga et al., 1998) 3. Rockland
4. Integration of long-distance and intrinsic connections Single axon reconstruction 3. Rockland 4. Silberberg Intrinsic micro-circuitry A cortical wiring diagram 2. Van Essen
Whole-cell recordings & Confocal connection analysis Touch Bouton • 5. Formation and plasticity of neural connections 4. Silberberg Tabula rasa Tension-based Cortical Folding 2. Van Essen