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Cannabis: A Unique Analgesic. Tod H. Mikuriya, M.D. California Cannabis Research Medical Group P.O Box 9143 Berkeley, CA 94709 WWW.CCRMG.ORG. Agitation, confusion progressing to sedation No Pupillary changes but injected sclera No respiratory effects No death.
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Cannabis: A Unique Analgesic Tod H. Mikuriya, M.D. California Cannabis Research Medical Group P.O Box 9143 Berkeley, CA 94709 WWW.CCRMG.ORG
Agitation, confusion progressing to sedation No Pupillary changes but injected sclera No respiratory effects No death Sedation, deepening unresponsiveness, coma Pin Point Pupils Respiratory depression Death Toxicity/OverdoseCannabis Opioids
Cannabis, an Antidepressant • Depression is a presenting feature of chronic disease pain. • Worsened by sedatives that decrease mobility and functionality • Not a sedative, cannabis increases mobility and functioning • Cannabis improves and normalizes sleep • Facilitates gastrointestinal functioning
Immunomodulator-Analgesic • Cannabinoids, unique non-watersoluble precursors of eicosanoids modulate both generalized and local inflammatory reactions through the prostaglandin systems. • Arthritic and neuritic inflammatory processes are relieved. • Involved in control of spasticity of inflammatory etiology
Antispasmodic • Both smooth and skeletal muscle spasm are eased by cannabis. • Peristalsis and glandular functioning are normalized by cannabis. • Both relief of spasm and promoting normal peristalsis and evacuation.
Cannabis, an easement • Not a narcotic • A mood modulator, a calmative that restores control at optimum dose. • Not a sedative when inhaled at low dose • An immunomodulator for generalized and local inflammatory processes • Antispasmodic smooth and skeletal muscle relaxant
Chronic Disease Pain Control • A mood modulator that both decreases emotional reactivity and vulnerability to pain by: • Controlling the immediate target symptom • Modulating emotional response • Promoting quality sleep • Normalizing gastrointestinal functioning
Antidepressant • Modulates and mobilizes emotional reactivity • Increases focus and concentration • Decreases distraction and intrusion of pain perception • Improves amount and quality of sleep to enhance cognition • Improves mobility and functioning • Restores a sense of control and self-esteem
Antidepressant Antispasmodic Appetite stimulant Promotes peristalsis Promotes evacuation Anti Pruritic Sedative Mild antispasmodic Appetite suppressant GERD and Gastritis Constipates Pruritic Cannabis Opioids