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Exercise at Altitude

Exercise at Altitude. Stress of Altitude Oxygen loading Oxyhemoglobin dissociation curve Mexico City Mt Everest. Acclimatization. Is the adaptive responses in physiology and metabolism that improves tolerance to altitude hypoxia Immediate and long term adjustments 2 weeks for 2300 m

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Exercise at Altitude

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  1. Exercise at Altitude • Stress of Altitude • Oxygen loading • Oxyhemoglobin dissociation curve • Mexico City • Mt Everest

  2. Acclimatization • Is the adaptive responses in physiology and metabolism that improves tolerance to altitude hypoxia • Immediate and long term adjustments • 2 weeks for 2300 m • Additional week for each 610 m

  3. Immediate-Pulmonary • Hyperventilation • Body fluids become more alkaline due to reduction in CO2

  4. Immediate-Cardiovascular • Increase in submax HR • Increase in submax CO • SV same or lower • Max CO remains the same or lower

  5. Long Term-Pulmonary • Hyperventilation • Excretion of base via Kidneys • Reduction of alkaline reserve

  6. Long Term-Cardiovascular • Submax HR elevated • Submax CO falls • SV lowers • Max CO lowers

  7. Long Term-Hematological • Decrease plasma volume • Increase hematocrit • Increase hemoglobin concentration • Increase number of RBC • Increased capillarization

  8. Long Term-Local • Increased RBC 2,3-DPG • Increased Mitochondria • Increased aerobic enzymes • Loss of body weight • Loss of lean body mass

  9. Medical Problems • Acute Mountain Sickness • High-Altitude Pulmonary Edema • High-Altitude Cerebral Edema

  10. Exercise Capacity • Aerobic Capacity is reduced 1.5-3.5% for every 305 meter increase above 1524 meters • Aerobic Capacity remains reduced even several months after acclimatization

  11. Altitude Training and Sea level Performance • VO2 max on return to sea level • No improvement • Reduction in Max CO offsets blood’s greater O2 carrying capacity • Can not train at same intensity of VO2 max • No difference between AT vs. Sea Level

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