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Medical Image Resource Center. What is MIRC?. “Medical Image Resource Center” Makes it easier to locate and share electronic medical images and related information On your PC In your Department Throughout the world. MIRC: Why?. MIRC can help:
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What is MIRC? • “Medical Image Resource Center” • Makes it easier to locate and share electronic medical images and related information • On your PC • In your Department • Throughout the world
MIRC: Why? • MIRC can help: • Teaching and decision support in clinical patient care • Make research databases more freely available to the imaging community • Clinical trials
The Evolution of MIRC • Originally conceived as a large database of images and related clinical information that would be maintained by the RSNA on one or more large servers for free access by the medical imaging community
The Evolution of MIRC • It soon become clear to us that a more effective strategy would be to: Create a standard that would tie together virtual communities of new and existing medical image libraries
Key MIRC Concepts • Libraries cooperate by supporting a common query mechanism. • A Query mechanism allows users to find information within these libraries • MIRC supports multiple information storage formats
MIRC Libraries • MIRC libraries archive a wide variety of text, images, and other multimedia information • Teaching files • Research and reference image repositories • Collection of disease specific radiographs • Normal variants • Functional brain MR data sets • Clinical trials images and related data • Journal articles • Textbooks • PowerPoint and other types of presentations
MIRC Components • Query Service Entry point into the MIRC community for a user on the Internet, Query service can be created by site using the MIRC query schema.
MIRC Components • Storage Service: Cooperating information library – a web archive or a database, designed to support the MIRC query mechanism. • Index: The library’s card catalog – an XML document that identifies content of a storage service. • Server: The library’s shelves – where the content of a MIRC site is stored or saved.
Index Server Index Server The MIRC Community User • MIRC Query Service: • Access to the community Internet Index MIRC Sites Server • MIRC Storage Service: • - Document Authoring • Document Storage • Document Indexing • Web Server RSNA
MIRC Query Service:User Fills in Query Form Need a new slide with Bobby’s new Query page
MIRC Query Results:Displays “Hits” from MIRC Sites Need a new slide with Bobby’s new Query Results page
MIRC Teaching File Display:MIRC-TF Display Format Maybe two or three screen shots in a stack showing the different display modes
MIRC Authoring Tools One or two slides showing the author service screens
MIRC Clinical Trials Features • Image acquisition from modalities and PACS • Image and metadata anonymization • Secure image and metadata transport • Automatic storage and indexing of all data, with the standard MIRC search and display functions • Interfacing to external databases for trial-specific analysis
MIRC Clinical Trial Configuration FC DICOM PI DICOM FC DICOM PI DICOM FC DICOM Modalities Firewalls Workstations Internet HTTP HTTPS • MIRC Site: • Image reception • Image Storage • Transfer to PACS and/or workstations • MIRC FieldCenter Application: • Image reception • Anonymization • Transmission to PI
MIRC in Clinical Trials • Comment on the NCI plans • Comment on other current trials using MIRC Something to show how MIRC is being used in clinical trials.
Open Source Project • All source code is available on-line • Zip archive through the RSNA MIRC site • CVS repository • Actively maintained MIRC project list • MIRC user meeting at RSNA2005 • Monday 1:30-3:00 E262 • Thursday 12:30-2:30 E257
The RSNA Teaching File Plans for the RSNA’s teaching file system, based on MIRC
How to Participate? • Use MIRC to perform searches for images and information • Be an author • Set up a MIRC site: • Connect your existing Teaching File system • Build your own Teaching File system: • Use the RSNA MIRC Site implementation • Use someone else’s • Come up with your own and make it MIRC compatible
Need More Information? • Go to http://mirc.rsna.org • There is a link to “Downloads” where you can find all the documents, software and installation instructions for setting up a MIRC site and creating content.
The rest of the slides are from the board presentation in case you might want to get some information from them
1. Public Internet MIRC Sites • Casimage (Switzerland) • Indiana University • Mallinckrodt • MedPix [RSNA] • MyPACS • National MIRC (Singapore) • Thomas Jefferson University [RSNA] • University of California at San Francisco • University of Padova (Italy) [RSNA] • GlobalRad
1. Private Intranet MIRC Sites • Bundeswehrzentralkrankenhaus Koblenz (Germany) • Children's Hospital of Philadelphia • Children's Hospital of Northwestern University • Cleveland Clinic • Geisinger Clinic • Mallinckrodt Institute of Radiology (research dataset acquisition) • Mass General (connected with University of Dusseldorf) • University of Alabama at Birmingham • University of California at San Diego • University of Dusseldorf • University of Maryland • University of Michigan (the largest site running RSNA code) • University of Pennsylvania (MJR Veterinary Hospital)
1. Far East MIRC Sites • National University Hospital, Singapore • Tan Tock Seng Hospital, Singapore • National Neuroscience Institute, Singapore [leader in the Far East] • Taiwan • PRC
2. NCI Collaboration • Successful demonstration in early 2005 • Support of current trials (RIDER, LIDC) • Decision to use MIRC in caBIG I2 project • Development of MIRC extensions to support the NCI imaging database
3. ACR Discussions • ACRIN clinical trials process for anonymizing and transferring images and associated data • Maintain consistency with NIH-NCI MIRC methodology • Major role in sharing of images and documentation for the review process in accreditation programs
Clinical Trials – WHIMS [1] • University of Pennsylvania (PI) • Wake Forest University (PI) • Central Massachusetts Imaging Center • Froedtert Pavilion • Jacksonville Medical Imaging • Montefiore Medical Center • Reno Diagnostic Imaging Center
Clinical Trials – WHIMS [2] • Stanford University • The Ohio State University • University Diagnostics MC (NY) • University of California at Davis • University of California at Los Angeles • University of Iowa • University of Florida
Clinical Trials – WHIMS [3] • University of Minnesota • University of North Carolina at Chapel Hill • University of Pittsburgh
Clinical Trials - WHI CT Study • WHI – Women’s Health Initiative CT Study – www.whi.org • 30 Field Centers in all • Sites using MIRC for transport: • Wake Forest University (PI) • Northwestern University and University of Illinois • University of Alabama at Birmingham • Kaiser (USCF) at Walnut Creek • University of Minnesota • All 30 sites’ images are entered into the PI MIRC site and processed.
Clinical Trials - CARDIA • Coronary Artery Risk Development in Young Adults • Wake Forest University (PI) • Northwestern University and University of Illinois • University of Alabama at Birmingham • Kaiser (USCF) at Walnut Creek • University of Minnesota
Clinical Trials – RIDER • Reference Image Database to Evaluate Response to Therapy • National Cancer Institute (PI) • Cornell University • MD Anderson Cancer Center • Memorial Sloan Kettering • University of California at Los Angeles • University of California at San Diego • University of Chicago • University of Iowa
Other Trials Using MIRC • CIREN – Crash Injury Research & Engineering Network • Wake Forest (PI) • CAMPS – Carotid Atherosclerosis MRI Progression Study • University of Washington (PI) • ACCORD – Action to Control Cardiovascular Risk in Diabetes • Case-Western University was used to test interfacing MIRC with ACRIN
Research Dataset Acquisition • MIRC feature developed with Mallinckrodt Institute of Radiology • Allows internal researchers to acquire DICOM images from modalities, store and manage them without using the clinical PACS • Bridges internal networks • Tracks access of PHI for HIPAA compliance
Research Dataset Acquisition Sites • Mallinckrodt Institute of Radiology • Wake Forest University • GCRC – WFUBMC General Clinical Research Center • CBI – WFUSM Center for Biomolecular Imaging • BME – WFUSM Dept Biomedical engineering • SBES – VT-WFU School of Biomedical Engineering and Sciences • WFUBMC – WFU Baptist Medical Center • Rad – WFUSM Dept of Radiology Oakland