Download
1 / 2
20 likes | 70 Views
WT. WT. WT. KO. KO. KO. Supplementary Figure 1. A. Body weight. B. Vision. C. Electroretinogram. D. Open field. Rotarod. E. p=0.34. 400. WT. WT. 17.5. 75. KO. KO. 15.0. 300. WT. 12.5. 50. KO. Body weight [g]. Preference [%]. Amplitude ( μ V ). Time [s]. 10.0.
E N D
WT WT WT KO KO KO Supplementary Figure 1 A Body weight B Vision C Electroretinogram D Open field Rotarod E p=0.34 400 WT WT 17.5 75 KO KO 15.0 300 WT 12.5 50 KO Body weight [g] Preference [%] Amplitude (μV) Time [s] 10.0 Amplitude [μV] 200 7.5 25 5.0 100 p=0.027 2.5 0 0.0 0 WT KO WT KO Periphery Intermediate Center Time [ms] Olfaction G Pain sensation H Hearing I Motivation J Prepulse inhibition F Startle 100 100 300 4 20 80 3 15 80 200 60 Sucrose consumption [%] 2 Inhibition [%] 10 Startle amplitude [au] Latency to find food [s] Latency [s] 40 60 100 1 5 20 0 0 0 40 0 60 80 1 2 3 4 70 75 80 100 120 KO WT KO WT dB Days dB
Supplementary Figure 2 WT WT KO KO C Open field D Open field E Open field F Vision G Olfaction 300 200 75 p=0.037 400 25 150 20 300 200 15 Preference [%] 100 50 200 Latency to periphery [s] Velocity [mm/s] Time [s] Latency to find food [s] 10 100 50 100 5 0 0 0 25 0 Periphery Intermediate Center WT KO WT KO WT KO WT KO B A Basic EPM EPM in darkness WT 300 300 KO p=0.03 p=0.0002 200 200 Time [s] Time [s] 100 100 0 0 Closed Center Open Closed Center Open
