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The 2 nd IGFD Forum. 13 th May 2009, Barcelona. Welcome & Objectives. Prof Martin Savage, Co-Chair. Sharing Clinical Experience & Opinions on Severe Primary IGF Deficiency (SPIGFD). Welcome to colleagues from Europe & US The 2 nd IGFD Forum: Opportunity to review latest data
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The 2nd IGFD Forum 13th May 2009, Barcelona
Welcome & Objectives Prof Martin Savage, Co-Chair
Sharing Clinical Experience & Opinions on Severe Primary IGF Deficiency (SPIGFD) • Welcome to colleagues from Europe & US • The 2nd IGFD Forum: • Opportunity to review latest data • Advice on identification & diagnosis of patients • Discussion on practical management of the condition • Above all, chance to share experience& exchange views in open discussion
The 2nd IGFD Forum • Since the 1st IGFD Forum in Chantilly in November 2007, clinicians have gained experience in diagnosis of SPIGFD and treatment with Increlex. We will draw on this experience. • Advances in three particular areas related to SIGFD; prevalence in short stature patients, genetic diagnoses, and new therapeutic studies with Increlex. • SPIGFD in the continuum of defects of the GH-IGF-I axis causing short stature.
Paradigm of GH secretion and GH sensitivity in short stature GH secretion Laron syndrome Severe Primary IGF-I Deficiency Idiopathic short stature GH secretion abnormalities GH Deficiency 0 GH sensitivity