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Developing magnetic resonance-based in-line sensors

Developing magnetic resonance-based in-line sensors. Michael J. McCarthy Department of Food Science & Technology. http://www.bruker-biospin.com/nmr_magnets_us2.html?&L=0&print=. NMR and MRI. Current Limitations: Not suitable for industrial environment Not portable Low sensitivity .

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Developing magnetic resonance-based in-line sensors

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  1. Developing magnetic resonance-based in-line sensors Michael J. McCarthy Department of Food Science & Technology

  2. http://www.bruker-biospin.com/nmr_magnets_us2.html?&L=0&print=http://www.bruker-biospin.com/nmr_magnets_us2.html?&L=0&print= NMR and MRI Current Limitations: Not suitable for industrial environment Not portable Low sensitivity • Strengths • - Chemical identification • - Structure determination • Medical imaging • Microscopy imaging • Noninvasive • High speed… Chocolate Milk 4 Averages Chocolate Milk 20 Averages Strawberry Milk

  3. Goals of our NMR work • Address current limitations and enable process NMR/MRI spectrometers for in-line control • Compatible with operation in an industrial environment • Small side streams • Larger installations for 100 % inspection • Rapid measurements of • Composition / quality attributes • Structure / Particle size, Rheological properties • Compatible with fluid food processing • Clean in place chemical • Liquid and particulate suspensions

  4. 2 T MRI system Enabling process NMR/MRI • Engineered materials • Novel magnets • Aspect AI • ABQMR Inc. • Miniaturization – NeSSI compatible • Microfabricated components • Dynamic nuclear polarization • Measurement information processing • Artificial intelligence, neural networks, chemometric methods

  5. Magnet Design Options 1 Tesla; ~0.4 sec scan • Higher magnetic field (~1.0 T) • Advantages • Signal-to-noise! (high speed) • Disadvantages • Cost • Weight • Imaging/nonimaging options • Low magnetic field strength (~0.05 to 0.2 T) • Advantages • Cost • Easier to integrate • Disadvantages • Signal-to-noise ratio (limits speed) • Imaging and/or nonimaging 0.1 T; 8 hour scan

  6. High Field System – Industrial System 1.0 Tesla No external field Industrial grade Large volume 1 Tesla Field Strength High performance Photos courtesy of ASPeCT Magnet Technologies Ltd. www.aspect-mr.com

  7. Example: Seed Detection 2. FSE 1. Turbo Flash

  8. Tomato concentrate viscosity to ketchup viscosity 1 (6 ounce) can tomato paste with garlic 1/2 cup light corn syrup 1/4 cup white vinegar 1/4 cup white balsamic vinegar 1/4 cup water 1 tablespoon sugar 1 teaspoon salt 1/4 teaspoon onion powder

  9. Measure tomato concentrate rheology

  10. Correlation of Ketchup Bostwick using in-line viscosity measurements of 12 Brix Tomato Concentrate Tomato ketchup Bostwick (cm) Tomato Concentrate (Viscosity/density)(-1/5)

  11. Portable low-field magnet Single-sided design 10.2 cm diameter 5.0 cm high 3.0 kilograms Proton frequency 5.2 MHz Measurement at 20 mm depth into melon (alternate designs yield up to 50 mm depth) Photo courtesy of ABQMR, Inc

  12. Miniaturizationmicro-NMR Incorporate DNP • Low field NMR Spectra • Benchtop/portable spectroscopy • Labscale system for metabolomics measurements • Microscale rheology

  13. DNP 110x to 200x Signal Enhancement x100

  14. Advanced in-line sensors for sorting fruit Using a Partial Least Squares-Discriminant Analysis applied to MRI data it is predicted that yields for the process can be increased by approximately 10% Good Whole Peel Pack Paste Production Sunburn Byproducts Rot Magnetic Resonance Imaging

  15. Summary • Novel permanent magnet designs extend applications of NMR/MRI from laboratory to the production line. • Microfabricated components are NeSSI scale compatible. • Permits quantitative quality standards and process control.

  16. Rebecca Milczarek Boaz Zion Paul Chen Sandra Garcia Songi Han Jeffrey Walton Eiichi Fukushima, ABQMR, Inc. Uri Rapoport, ASPECT Magnet Technologies Ltd. www.aspect-mr.com USDA USDA-BARD CDFA Citrus Research Board Avocado Commission ConAgra Foods Paramount Citrus Association CPAC Acknowledgements

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