1 / 2

Antibody Drug Conjugates Against Tumor Stroma: What Can We Do?

Antibody-drug Conjugates or ADCs are highly targeted biopharmaceutical drugs that combine monoclonal antibodies specific to surface antigens present on particular tumor cells with highly potent anti-cancer agents linked via a chemical linker. The linker plays a key role in determining the pharmacokinetic properties, therapeutic index, selectivity and the overall success of the ADC.

sunnyfang1419
Download Presentation

Antibody Drug Conjugates Against Tumor Stroma: What Can We Do?

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Biochempeg https://www.biochempeg.com Antibody Drug Conjugates Against Tumor Stroma: What Can We Do? Antibody-drug Conjugates or ADCs are highly targeted biopharmaceutical drugs that combine monoclonal antibodies specific to surface antigens present on particular tumor cells with highly potent anti-cancer agents linked via a chemical linker. The linker plays a key role in determining the pharmacokinetic properties, therapeutic index, selectivity and the overall success of the ADC. PEG-linkers are particularly attractive as a linker for conjugation. Water solubility, lack of toxicity; low immunogenicity and well defined chain lengths and molecular weights are specific characteristics of PEG moieties relevant to pharmaceutical applications. Biochempeg develops a broad range of PEG linkers and provides custom linker synthesis for clients worldwide.

  2. Biochempeg https://www.biochempeg.com

More Related