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A. Foxm1 -/- MEFs. WT MEFs. Foxm1 mRNA. Brip1 mRNA. Plk mRNA. FOXM1 . **. **. *. ***. BRIP1 . Normalised mRNA level. PLK . β - Tubulin. WT MEFs. WT MEFs. WT MEFs. Foxm1 -/- MEFs. Foxm1 -/- MEFs. Foxm1 -/- MEFs. B. WT MEFs. Foxm1 -/- MEFs. Epirubicin (0.1 µM):.
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A. Foxm1-/- MEFs WT MEFs Foxm1 mRNA Brip1 mRNA Plk mRNA FOXM1 ** ** * *** BRIP1 Normalised mRNA level PLK β-Tubulin WT MEFs WT MEFs WT MEFs Foxm1-/-MEFs Foxm1-/- MEFs Foxm1-/-MEFs B. WT MEFs Foxm1-/- MEFs Epirubicin (0.1 µM): 0 0 0.5 4 24 0.5 4 24 (h) FOXM1 BRIP1 β-Tubulin Brip1 mRNA Foxm1 mRNA Normalised mRNA level * ** *** *** *** *** *** *** 0.5 4 24 0.5 4 24 (h) 0 0 0.5 4 24 0.5 4 24 (h) 0 0 Epirubicin: (0.1M) Foxm1-/-MEFs WT MEFs Foxm1-/-MEFs WT MEFs Supplementary Fig. S4