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Discover the fascinating process of protein synthesis, from transcribing DNA to forming proteins through translation. Follow the journey of amino acids as they are built into proteins.
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Protein Synthesis Define- building aminoacids into proteins. • Transcription- the code on the DNA is transferred to the RNA • T A C C G G C T A T A T A G C G A A • A T G G C C G A T A T A T C G C T T • T A C C G G C T A T A T A G C G A A • A U G G C C G A U A U A U C G C U U DNA DNA mRNA
2. The mRNA then leaves the nucleus and attaches to the ribosome in the cytoplasm • A U G G C C G A U A U A U C G C U U mRNA Ribosome
CGG CGG UAC CUA CUA CUA UAC 3. Aminoacids in the cytoplasm are picked up by specific tRNA molecules Alanine Alanine Methionine Aspartic Acid Aspartic Acid
Alanine CGG CGG Methionine UAC CUA CUA CUA UAC 3. Aminoacids in the cytoplasm are picked up by specific tRNA molecules Alanine Methionine Aspartic Acid Aspartic Acid
Alanine CGG CGG Methionine UAC Aspartic Acid CUA CUA CUA UAC 3. Aminoacids in the cytoplasm are picked up by specific tRNA molecules Alanine Methionine Aspartic Acid Aspartic Acid
Alanine CGG Methionine UAC 4. The tRNA molecules then bring the aa’s to the ribosome in the correct order as designated by the mRNA A U G G C C G A U A U A U C G C U U mRNA Ribosome
Alanine CGG Methionine CUA UAC 5. Translation- the aa’s from each tRNA attach to one another at the ribosome mRNA A U G G C C G A U A U A U C G C U U Ribosome
Alanine CGG Methionine Aspartic Acid CUA UAC 5. Translation- the aa’s from each tRNA attach to one another at the ribosome mRNA A U G G C C G A U A U A U C G C U U Ribosome
Alanine Methionine 6. The tRNA molecules leave the aa’s and go back to the cytoplasm A U G G C C G A U A U A U C G C U U Ribosome 7. Once the aa’s are attached to one another, the ribosome releases this protein into the cytoplasm
Alanine Methionine Aspartic Acid A U G G C C G A U A U A U C G C U U 6. The tRNA molecules leave the aa’s and go back to the cytoplasm Ribosome 7. Once the aa’s are attached to one another, the ribosome releases this protein into the cytoplasm
Alanine Methionine Aspartic Acid Isoleucine A U G G C C G A U A U A U C G C U U 6. The tRNA molecules leave the aa’s and go back to the cytoplasm Ribosome 7. Once the aa’s are attached to one another, the ribosome releases this protein into the cytoplasm
Alanine Methionine Aspartic Acid Isoleucine Serine A U G G C C G A U A U A U C G C U U 6. The tRNA molecules leave the aa’s and go back to the cytoplasm Ribosome 7. Once the aa’s are attached to one another, the ribosome releases this protein into the cytoplasm
Alanine Methionine Aspartic Acid Isoleucine Serine Leucine A U G G C C G A U A U A U C G C U U Ribosome 6. The tRNA molecules leave the aa’s and go back to the cytoplasm 7. Once the aa’s are attached to one another, the ribosome releases this protein into the cytoplasm
Review it! • 500 x 3 = 1500 pairs • 43 = 64 • AUG-UUA-AAG-CUG-CAG-CAG-UAU-CUU-CUC-CCC • met-leu-lys-leu-glu-glu-tyr-leu-leu-pro • UGG (mRNA) ACC (DNA) • 6 • CGU-CGC-CGA-CGG-AGA-AGG • ATG –TAC- CGT- GTC- CAG- CAC- TTG -GGC -ACG • AUG –UAC-CGU-GUC-CAG –CAC- UUG -GGC -ACG met-tyr-arg-val-glu-his-leu-gly-thr