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  1. Figure 1S – Growth phenotypes of IM69 (∆atmA), MV3 (∆npkA), IM69-3 (∆atmA ∆npkA), MRE (mreA::pyr4), IM69-RE (∆atmA mreA::pyr4), APk35 (ankA), IM69-35 (∆atmA ankA), A776 (bimE7), and IM69-228 (∆atmA bimE7). Conidia from these strains were inoculated and percentage of radial growth inhibition was evaluated after growth for 72 hours at 30oC. The results are the average of four repetitions.

  2. A. ∆atmA ∆atmA ∆npkA mreAMRE11 ∆atmA mreAMRE11::pyr4 ∆atmA ∆npkA 100 100 80 80 Radial Growth (%) 60 Radial Growth (%) 60 40 40 20 20 0 0 0 10.0 1.0 2.5 7.5 5.0 0 10.0 1.0 2.5 7.5 5.0 HU (mM) HU (mM) ∆atmA ∆atmA bimE7 ankA ∆atmA bimE7 ∆atmA ankA 100 100 80 80 Radial Growth (%) 60 Radial Growth (%) 60 40 40 20 20 0 0 0 0 10.0 10.0 1.0 2.5 7.5 1.0 2.5 7.5 5.0 5.0 HU (mM) HU (mM)

  3. B. ∆atmA ∆atmA mreAMRE11::pyr4 ∆npkA ∆atmA mreAMRE11::pyr4 ∆atmA ∆npkA 100 100 80 80 60 Radial Growth (%) Radial Growth (%) 60 40 40 20 20 0 0 10.0 1.0 2.5 5.0 7.5 0 10.0 1.0 2.5 5.0 7.5 0 MMS (X 10-3 %) MMS (X 10-3 %) ∆atmA ∆atmA bimE7 ankA ∆atmA bimE7 ∆atmA ankA 100 100 80 80 Radial Growth (%) 60 Radial Growth (%) 60 40 40 20 20 0 0 10.0 10.0 1.0 2.5 5.0 7.5 0 1.0 2.5 5.0 7.5 0 MMS (X 10-3 %) MMS (X 10-3 %)

  4. C. ∆atmA ∆atmA ∆npkA mreAMRE11::pyr4 ∆atmA ∆npkA ∆atmA mreAMRE11::pyr4 100 100 80 80 Radial Growth (%) Radial Growth (%) 60 60 40 40 20 20 0 0 0 0.005 0.01 0.05 0.1 0 0.005 0.01 0.05 0.25 0.1 0.25 4-NQO (g/ml) 4-NQO (g/ml) ∆atmA ∆atmA ankA bimE7 ∆atmA ankA ∆atmA bimE7 100 100 80 80 Radial Growth (%) 60 60 Radial Growth (%) 40 40 20 20 0 0 0 0.005 0.01 0.05 0.1 0.25 0 0.005 0.01 0.05 0.1 0.25 4-NQO (g/ml) 4-NQO (g/ml)

  5. D. ∆atmA ∆atmA ∆npkA mreAMRE11::pyr4 ∆atmA mreAMRE11::pyr4 ∆atmA ∆npkA 100 100 80 80 Radial Growth (%) Radial Growth (%) 60 60 40 40 20 20 0 0 10 10 25 25 5 50 5 50 0 0 75 75 CPT (M) CPT (M) ∆atmA ∆atmA ankA bimE7 ∆atmA ankA ∆atmA bimE7 100 100 80 80 Radial Growth (%) 60 60 Radial Growth (%) 40 40 20 20 0 0 10 25 5 50 0 10 75 25 5 50 0 75 CPT (M) CPT (M)

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