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Muscle Fiber Structure. Muscle- >Fascicle->Fiber->Myofibril->Filaments Fascia – A layer of connective tissue that separates muscles and holds muscles in place. Muscle-> Fascicle ->Fiber->Myofibril->Filaments Fascicle – A bundle of muscle cells
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Muscle->Fascicle->Fiber->Myofibril->Filaments • Fascia – A layer of connective tissue that separates muscles and holds muscles in place
Muscle->Fascicle->Fiber->Myofibril->Filaments • Fascicle – A bundle of muscle cells • Epimysium – A layer of connective tissue that closely surrounds a skeletal muscle • Perimysium – Another layer of connective tissue that extends inward and separates the fascicles
Muscle->Fascicle->Fiber->Myofibril->Filaments • Fiber – A muscle cell, very long and thin • Sarcolemma – Cell membrane of a muscle cell • Sarcoplasm – Cytoplasm of a muscle cell • Sarcoplasmic Reticulum – Endoplasmic Reticulum of a muscle cell • Transverse (T) Tubule – Membranous channels that extend into the sarcoplasm from invaginations in the sarcolemma, assist with action potential movement
Muscle->Fascicle->Fiber->Myofibril->Filaments • Myofibril – A bundle of thick and thin filaments (proteins) • Myosin – A protein that makes up thick filaments • Actin – A protein that makes up thin filaments • Troponin – Attached to actin, made of 3 protein subunits • Tropomyosin – Attached to actin, longtitudinal Thin Filaments Thick Filament
Muscle->Fascicle->Fiber->Myofibril->Filaments • Sarcomere – Alternating patterns of myosin and actin, creates striations in cardiac and skeletal muscle • I bands – Light bands, made of thin filaments (actin), anchored by Z lines • A bands – Dark bands, made of thick filaments (myosin), anchored by M lines, thick and thin filaments overlap in this area • H Zone – Area where only thick filaments exist