1 / 10

Type 2 Diabetes and Obesity

Type 2 Diabetes and Obesity. California State University San Marcos Kim Jeffrey Sallie Rucker Alyssa Wooten. 90-95% of all diagnosed cases are type 2 and most often associated with old age, family history of the disease, level of physical activity, and certain ethnicities.

tamarr
Download Presentation

Type 2 Diabetes and Obesity

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Type 2 Diabetes and Obesity California State University San Marcos Kim Jeffrey Sallie Rucker Alyssa Wooten

  2. 90-95% of all diagnosed cases are type 2 and most often associated with old age, family history of the disease, level of physical activity, and certain ethnicities. The 7th leading cause of death listed on US death certificates. Number of people diagnosed in 1958: 1.5 million Number of people diagnosed in 2007: 17.9 million Total health care related costs for treatment is $174 billion annually Type 2 Diabetes Statistics

  3. Physiology of Type 2 Diabetes • Type 2 is associated with insulin resistance • When there is not enough insulin or insulin is not used as it should be, glucose cannot get into the cells, causing the cells to not function properly. http://www.medicinenet.com/script/main/art.asp?articlekey=42940

  4. Physiology (continued) • Insulin- key component, necessary in order for the body to convert glucose into energy. • 2 problems: cells starve for energy; prolonged high levels of glucose cause damage to kidneys, eyes, heart, nerves. http://diabetes.about.com/od/symptomsdiagnosis/a/obesity.htm?p=1

  5. Medical Breakthroughs • Researchers at UBC along with Washington University in St. Louis discovered protein called Carboxypeptidase E (CPE) • CPE is a protein in beta cells of pancreas • Key role in producing insulin, not previously explored as possible cause of insulin failure

  6. Medical Breakthroughs (continued) • Researchers used new technology called proteomics • Proteomics shows that fats can reduce levels of CPE • Reduction of CPE causes beta cells to become clogged & causes non-functioning insulin to be produced

  7. New Findings • Johns Hopkins Medicine: • Fat cells secrete hormone-like substances in blood stream • 3 substances made by fat cells • Resistin, leptin, & free fatty acids • Accumulation of fatty acids in muscle cells of obese may prevent glucose from entering cells - rise in BGL http://www.walgreens.com/marketing/library/graphics/images/en/19267.jpg

  8. Prevention • Finnish study- 522 obese men, 55 y/o, IGT • Individual weight loss training, increased physical activity, food intake management • 3 yrs, 58% reduction • Similar study done by Diabetes Prevention Program- same results

  9. 3 prevention trials: metformin (31%), accarbose (32%), thiazolidione troglitazone (T.T) (56%) More research on T.T- possible true prevention action Best treatment: lifestyle change Balanced diet Regular physical activity Monitor sugar intake If diagnosed, can still live long life as long as one maintains a healthy lifestyle Pharmacological Interventions Conclusion

  10. References • American Diabetes Association and National Institute of Diabetes, Digestive and Kidney Diseases. (2002). The prevention or delay of type 2 diabetes. Diabetes Care, 25(4), 742-749. • Diabetes: type 2 diabetes. (2009). Retrieved October 17, 2009, from http://www.medicinenet.com/script/main/art.asp?articlekey=42940 • Diabetes overview. (2008, November). Retrieved October 14, 2009, from http://www.diabetes.niddk.nih.gov/dm/pubs/overview/index.htm • National diabetes education program. (2009). Retrieved October 16, 2009, from http://www.ndep.nih.gov/diabetes-facts/index.aspx • New link between obesity and type 2 diabetes: researchers discover new way fat kill beta-cells. (2008, June 4). Retrieved October 12, 2009, from http://www.physorg.com/print131814266.html • Type 2 diabetes. (2000, September). Retrieved October 12, 2009, from http://www.diabetes.org/type-2-diabetes.jsp • Why obesity contributes to type 2 diabetes. (2009). Retrieved October 13, 2009, from http://www.johnshopkinshealthalerts.com/report/diabetes

More Related