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8th Consortium Meeting. WP 1.3 Quality and assessment. Hans-Peter Eich, Michael Wenzel. Coordination Centre for Clinical Trials, Heinrich-Heine-University, Düsseldorf, Germany. www.infobiomed.net. Amsterdam, The Netherlands, May 08 to 09, 2006. WP 1.3 Quality and assessment. Objectives
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8th Consortium Meeting WP 1.3 Quality and assessment Hans-Peter Eich, Michael Wenzel Coordination Centre for Clinical Trials, Heinrich-Heine-University, Düsseldorf, Germany www.infobiomed.net Amsterdam, The Netherlands, May 08 to 09, 2006
WP 1.3 Quality and assessment • Objectives • Assessment of results obtained within WP 6 (pilot application) • Specific objectives • Assessment of the validity of tools and methodologies used • Assessment of functionality and user-interface • Potential use • Evaluation of network www.infobiomed.net Amsterdam, The Netherlands, May 08 to 09, 2006
WP 1.3 Quality and assessment • Evaluation Protocol- goal • - components • patient / genomic data • methods / procedures • parameters to observe • evaluators Procedure Preparation Report on evaluation strategies Performance • Evaluation Report- statistical analysis • results • - discussion Analysis Report on evaluation results www.infobiomed.net Amsterdam, The Netherlands, May 08 to 09, 2006
Description of evaluation procedure www.infobiomed.net Amsterdam, The Netherlands, May 08 to 09, 2006
WP 6.1 Pharmainformatics I www.infobiomed.net Amsterdam, The Netherlands, May 08 to 09, 2006
WP 6.1 Pharmainformatics II www.infobiomed.net Amsterdam, The Netherlands, May 08 to 09, 2006
WP 6.1 Pharmainformatics III filtering list by ATC codes List of NFB targets 204 ATC codes Removal of Drugs for Topic Use and Rank List by Frequency in case-control set Rank by potency against pathway 127 ATC codes Final List of Drugs Relative Risk Assessment Novel or classical approach ? New Treatment Options for CRPS www.infobiomed.net Amsterdam, The Netherlands, May 08 to 09, 2006
WP 6.2 Genomics and microbiology I www.infobiomed.net Amsterdam, The Netherlands, May 08 to 09, 2006
WP 6.2 Genomics and microbiology II www.infobiomed.net Amsterdam, The Netherlands, May 08 to 09, 2006
WP 6.2 Genomics and microbiology III Core interferon genes/ 200 CMV proteins Protein Interaction prediction (PIANA) Potential biomarker Drugability analysis predicted biomarker Novel or classical approach? www.infobiomed.net Amsterdam, The Netherlands, May 08 to 09, 2006
WP 6.3 Genomics and chronic inflammation I www.infobiomed.net Amsterdam, The Netherlands, May 08 to 09, 2006
WP 6.4 Genomics and colon cancer I www.infobiomed.net Amsterdam, The Netherlands, May 08 to 09, 2006
WP 6.4 Genomics and colon cancer II www.infobiomed.net Amsterdam, The Netherlands, May 08 to 09, 2006
Network Evaluation Procedure I • Methods • Multi-graph analysis • Exchange of staff, knowledge transfer, communication • Information gathering via questionnaire www.infobiomed.net Amsterdam, The Netherlands, May 08 to 09, 2006
Network Evaluation Procedure II Communication Travel/Staff Transfer Knowledge www.infobiomed.net Amsterdam, The Netherlands, May 08 to 09, 2006
Network Evaluation Procedure III Merging types of information Detection of clusters merged www.infobiomed.net Amsterdam, The Netherlands, May 08 to 09, 2006
Timeline www.infobiomed.net Amsterdam, The Netherlands, May 08 to 09, 2006