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Objectives. Overview of General Pharmacology Develop a Basic Knowledge of medications used by BLS Providers Identify situations when each medication may be indicated. General Pharmacology. For every medication you may administer, you must thoroughly understand the following:. Actions
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Objectives • Overview of General Pharmacology • Develop a Basic Knowledge of medications used by BLS Providers • Identify situations when each medication may be indicated
General Pharmacology • For every medication you may administer, you must thoroughly understand the following: • Actions • Indications • Contraindications • Dosage • Route • Side effects
General Pharmacology • Right Time • Right Patient • Right Drug • Right Dose • Right Route
Generic name Original chemical name Trade name Brand name given by manufacturer General Pharmacology
General Pharmacology Dosage Forms • Solutions • Liquid mixture of one or more substances • Nebulized Solution • Pressurized gas passed over a solution to create an aerosol mist, which is then inhaled
Anaphylaxis Epinephrine for BLS Providers
An exaggerated immune response to an allergen Sudden, rapid onset Systemic involvement Severe allergic reaction Anaphylaxis
Very Common Range from mild and local to severe and systemic. Mild reactions usually affect only one area of the body Slow onset, and minor symptoms Allergic Reactions
Mild Allergic Reactions A mild, local reaction caused by a bee sting
A Clear History of Allergen Exposure AND Signs and Symptoms including: Shock (hypoperfusion) Respiratory Distress Wheezing, stridor, cough Chest / throat tightness Severe Allergic Reaction
Severe Allergic Reaction • Itching, skin flushing • Hives and/or swelling • (esp. face, extremities)
Severe Allergic Reaction • Increased Pulse • Decreased Blood Pressure • Nausea & Vomiting • Altered Mental Status • Allergen exposure with history of anaphylaxis
Patient History • Determine if the patient’s history includes: • Anaphylaxis • Severe allergic reactions • Recent exposure to a known or potential allergen
Focused Physical Assessment • Assess ABCs • Breath Sounds • Vital Signs • O2 Saturation • Assess Respiratory System • Assess Cardiovascular System • Assess for Signs & Symptoms of Anaphylaxis
Epinephrine • Generic Name • Epinephrine • Trade Name • EpiPen • EpiPen Jr. • Also called • Adrenalin
EpinephrineActions • Dilates Bronchioles • Constricts Blood Vessels
EpinephrineIndications • Signs and Symptoms of Severe Allergic Reaction
EpinephrineContraindications • None BUT MUST FOLLOW NYS PROTOCOLS!
EpinephrineDosage • Adult • One Adult Auto-injector (0.3 mg) • Infant and Child (< 9 y/o or < 30 kg / 66 lbs.) • One Infant/Child Auto-injector (0.15 mg)
EpinephrineRoute • Deep Intramuscular Injection • Lateral thigh, midway between waist and knee
Increased pulse rate Pallor Dizziness Chest Pain EpinephrineSide Effects • Headache • Nausea • Vomiting • Excitability • Anxiety
Epi auto-injectorProtocol • Call ALS • Administer Oxygen • Assess Respiratory Status • Assess Cardiac Status
Epi auto-injectorProtocol If the patient has an epi auto-injector prescribed: • assist the patient in administering the auto-injector
Epi auto-injectorProtocol • If the patient’s epi auto-injector is not available or expired: • Administer the agency’s epi auto-injector Per Protocol
Epi auto-injectorProtocol If no epi auto-injector has been prescribed: • Begin transport • Contact medical control for authorization to administer the agency’s epi auto-injector
Epi auto-injectorProtocol If unable to contact Medical Control, and patient isless than 35 years of age: • Administer agency supplied epi auto-injector per protocol • Contact Medical Control ASAP
What IsMedical Control? • A REMO Physician • If no REMO Physician is available, contact ED Physician at the Destination Hospital • Document WHO you talked to
Epi auto-injectorProtocol • Medical Control MUST be contacted to administer a second auto-injector. • Be prepared to perform CPR if patient deteriorates. • Document history, vitals, and treatment on PCR.
Summary: ALS must be called Contact Medical Control If Medical Control unavailable and patient is <35 years old, administer epi auto-injector Epi auto-injectorProtocol
Epi auto-injector Administration • Remove safety cap from auto-injector • Hold auto-injector from center (DoNot place thumb over either end!) • Place against patient’s thigh • Lateral portion, midway between waist and knee
Epi auto-injector Administration • Push until auto-injector activates • Hold until medication injected (10 seconds). • Record Time • Record Response • Dispose of auto-injector in biohazard “sharps” container.
Reassessment Strategy • Monitor A-B-Cs • Reassess Vitals • Oxygen! • Watch for changes in Patient Condition
If the patient deteriorates... Oxygenate Contact Medical Control for order for second dose Prepare for resuscitation Oxygenate Treat for shock ReassessmentStrategy Oxygenate Did we mention Oxygenate?
Asthma Albuterol for BLS Providers
Asthma • A common but serious disease • Affects more than 10 million Americans. • Kills 4000 to 5000 Americans annually.
Asthma • Reversible smooth muscle spasm of the airway (bronchospasm) associated with hypersensitivity to various stimuli
Allergy Aspiration Exertion Infection Stress Temperature change Seasonal changes Bronchospasm Triggers
Signs and Symptoms Dyspnea Wheezing Tachypnea Tachycardia Cyanosis Cough Asthma
Signs and Symptoms (cont.) Accessory muscle use Inability to speak in complete sentences Anxiety (hypoxia) Prolonged expiratory phase Tripod positioning Asthma
O P Q R S T Patient History • S • A • M • P • L • E
Patient History • Confirm Asthma History • “All That Wheezes Is Not Asthma” • Hospital visits for asthma in past year? • Any previous intubations due to asthma?
Position found Pursed lip breathing Vital signs Ability to speak in complete sentences Accessory muscle use Physical Exam
Physical Exam • Lung Sounds • Wheezing may or may not be present • Wheezes may be audible with or without a stethoscope • Decreased breath sounds (poor air movement) • Patient’s self-assessment • (0-10 scale)
Generic Name Albuterol Trade Names Proventil Ventolin Albuterol
AlbuterolActions • Bronchodilation • Duration of effect is up to five hours.
History of Asthma Respiratory Distress AlbuterolIndications
Known hypersensitivity to albuterol Respiratory Failure AlbuterolContraindications
AlbuterolDosage • Single-dose solution of 2.5 mg in 3 ml of normal saline for use in small volume nebulizer
AlbuterolRoute By Mouthpiece Nebulized Medication By Mask